A
Amit Gupta
Researcher at All India Institute of Medical Sciences
Publications - 195
Citations - 1395
Amit Gupta is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Trauma center & Oxidative stress. The author has an hindex of 15, co-authored 189 publications receiving 1044 citations. Previous affiliations of Amit Gupta include Alfred Hospital & Panjab University, Chandigarh.
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Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.
TL;DR: The neuroprotective potential of statins in experimental model of 6-OHDA induced Parkinson like symptoms is demonstrated and restored mitochondrial enzyme complex activities and attenuated neuroinflammatory markers in 6- OHDA treated animals as compared to control group.
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Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model.
TL;DR: It is suggested that during immunological activation, there is significant increase in oxidative stress and curcumin can be a valuable option in the treatment of chronic fatigue syndrome.
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Paclitaxel-loaded solid lipid nanoparticles modified with Tyr-3-octreotide for enhanced anti-angiogenic and anti-glioma therapy.
Indranil Banerjee,Kakali De,Dibyanti Mukherjee,Goutam Dey,Sankha Chattopadhyay,Manabendra Mukherjee,Mahitosh Mandal,Amal Kumar Bandyopadhyay,Amit Gupta,Santanu Ganguly,Mridula Misra +10 more
TL;DR: It is found that PSM improved anti-cancer efficacy of paclitaxel in SSTR2 positive glioma of rats, and this improvedAnti-glioma efficiency can be attributed to dual-targeting (i.e. tumor cell and neovasculature targeting) efficiency of PSM and promoted anti- cancer drug accumulation at tumor site due to TOC modification of solid lipid nanoparticles.
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Findings of the International Nosocomial Infection Control Consortium (INICC), Part I: Effectiveness of a Multidimensional Infection Control Approach on Catheter-Associated Urinary Tract Infection Rates in Pediatric Intensive Care Units of 6 Developing Countries
Victor D. Rosenthal,Bala Ramachandran,Lourdes Dueñas,Carlos Alvarez-Moreno,Josephine Anne Navoa-Ng,Alberto Armas-Ruiz,Gülden Ersöz,Lorena Matta-Cortés,M. Pawar,A. Nevzat-Yalcin,Marena Rodríguez-Ferrer,Ana Concepción Bran de Casares,Claudia Linares,Victoria D. Villanueva,Roberto Campuzano,Ali Kaya,Luis F. Rendón-Campo,Amit Gupta,Özge Turhan,Nayide Barahona-Guzmán,Lilian de Jesús-Machuca,María Corazon V Tolentino,Jorge Mena-Brito,Necdet Kuyucu,Yamileth Astudillo,Narinder Saini,Nurgul Gunay,Guillermo Sarmiento-Villa,Eylul Gumus,Alfredo Lagares-Guzmán,Oguz Dursun +30 more
TL;DR: It is demonstrated that implementing a multidimensional infection control approach is associated with a significant reduction in the CAUTI rate of PICUs in developing countries.
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30-Day In-hospital Trauma Mortality in Four Urban University Hospitals Using an Indian Trauma Registry
Nobhojit Roy,Martin Gerdin,Samarendra Nath Ghosh,Amit Gupta,Vineet Kumar,Monty Khajanchi,Eric B. Schneider,Russell L. Gruen,Göran Tomson,Johan von Schreeb +9 more
TL;DR: Using a multi-institutional Indian registry, this study is the first to systematically document that the 30-day in-hospital trauma mortality was twice that found in similar registries from high-income countries.