Victor D. Rosenthal

TL;DR: This study provides the first comprehensive assessment of the global burden of AMR, as well as an evaluation of the availability of data, and estimates aggregated to the global and regional level.

TL;DR: The frequencies of resistance of Staphylococcus aureus isolates to methicillin (MRSA), Klebsiella pneumoniae to ceftazidime or ceftriaxone, Acinetobacter baumannii to imipenem, and Pseudomonas aeruginosa to piperacillin were far higher in the consortium's ICUs than in comparable US ICUs.

TL;DR: Device-associated infections, particularly ventilator-associated pneumonia, central venous catheterrelated bloodstream infections, and catheter-associated urinary tract infections pose the greatest threat to patient safety in the ICU, according to the initial findings of an International Nosocomial Infection Control Consortium (INICC) surveillance study.

TL;DR: During the 6-year study period, using Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN; formerly the National Nosocomial Infection Surveillance system [NNIS]) definitions for device-associated health care-associated infections, prospective data was gathered from 313,008 patients hospitalized in the consortium's ICUs for an aggregate of 2,194,897 ICU bed-days.

TL;DR: A program consisting of focused education and frequent performance feedback produced a sustained improvement in compliance with hand hygiene, coinciding with a reduction in nosocomial infection rates in the ICUs.