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Amit P. Jathoul
Researcher at Cardiff University
Publications - 21
Citations - 1008
Amit P. Jathoul is an academic researcher from Cardiff University. The author has contributed to research in topics: Luciferase & Bioluminescence. The author has an hindex of 10, co-authored 20 publications receiving 851 citations. Previous affiliations of Amit P. Jathoul include University College London & Defence Science and Technology Laboratory.
Papers
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Journal ArticleDOI
Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter
Amit P. Jathoul,Jan Laufer,Jan Laufer,Jan Laufer,Olumide Ogunlade,Bradley E. Treeby,Ben T. Cox,Edward Z. Zhang,Peter Johnson,Arnold Pizzey,Brian Philip,Teresa Marafioti,Mark F. Lythgoe,R. Barbara Pedley,Martin Pule,Paul C. Beard +15 more
TL;DR: Deep photoacoustic imaging of mammalian cells featuring genetically encoded contrast is reported, and the results are reported to be consistent with previous studies of this type of imaging.
Journal ArticleDOI
Red-emitting luciferases for bioluminescence reporter and imaging applications.
Bruce R. Branchini,Danielle M. Ablamsky,Audrey L. Davis,Tara L. Southworth,Braeden L. Butler,Frank Fan,Amit P. Jathoul,Martin Pule +7 more
TL;DR: The results suggest that the novel enzymes should provide superior performance in dual-color reporter and in vivo imaging applications, and they illustrate the importance of codon optimization for assays in mammalian cells.
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A Dual-Color Far-Red to Near-Infrared Firefly Luciferin Analogue Designed for Multiparametric Bioluminescence Imaging
TL;DR: This work has synthesized and tested the first dual-color, far-red to near-infrared (nIR) emitting analogue of beetle luciferin, which, akin to natural lucifer in, exhibits pH dependent fluorescence spectra and emits bioluminescence of different colors with different engineered Fluc enzymes.
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An MRAS, SHOC2, and SCRIB Complex Coordinates ERK Pathway Activation with Polarity and Tumorigenic Growth
Lucy C. Young,Nicole Hartig,Marta Munoz-Alegre,Juan A. Oses-Prieto,Sevi Durdu,Sabine Bender,Vineetha Vijayakumar,Matteo Vietri Rudan,Christina Gewinner,Stephen Henderson,Amit P. Jathoul,Rupinder Ghatrora,Mark F. Lythgoe,Alma L. Burlingame,Pablo Rodriguez-Viciana +14 more
TL;DR: In this paper, the authors show that SHOC2 and MRAS form a complex with SCRIB, a polarity protein with tumor suppressor properties, and that this complex plays a key role during tumorigenic growth.
Journal ArticleDOI
In vitro characterization of genetically expressed absorbing proteins using photoacoustic spectroscopy.
TL;DR: This study suggests that chromoproteins may have potential for providing genetically encoded photoacoustic contrast, by synthesizing and characterizing a range of commonly used fluorescent proteins and novel non-fluorescent chromoprotein and genetic expression of a chromop protein in mammalian cells.