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Amos Gilhar

Researcher at Technion – Israel Institute of Technology

Publications -  149
Citations -  5013

Amos Gilhar is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Alopecia areata & Hair loss. The author has an hindex of 38, co-authored 136 publications receiving 4450 citations. Previous affiliations of Amos Gilhar include Rambam Health Care Campus & University of Utah.

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Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis.

TL;DR: The inhibitory effects of apremilast on pro‐inflammatory responses of human primary peripheral blood mononuclear cells, polymorphonuclear Cells, natural killer cells and epidermal keratinocytes were explored in vitro, and in a preclinical model of psoriasis.
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Lymphocytes, neuropeptides, and genes involved in alopecia areata

TL;DR: The role of HLA associations, other immunogenetic factors, and neuroendocrine parameters in alopecia areata pathogenesis are reviewed and this instructive and clinically significant model disease deserves more widespread interest in the immunology community.
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Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice.

TL;DR: Data indicate that alopecia areata is mediated by T cells which recognize a follicular autoantigen, and this disease is often psychologically devastating.
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Alopecia Areata: A tissue specific autoimmune disease of the hair follicle

TL;DR: Evidence is presented suggesting that alopecia areata results from loss of immune privilege with presentation of autoantigens, a powerful model for study of the induction and pathogenesis of tissue directed autoimmune disease.
Journal Article

Enhancing the take of injected adipose tissue by a simple method for concentrating fat cells.

TL;DR: This method was found to be simple, cheap, and friendly to the surgeon in comparison with traditional processing using the centrifuge, and significantly less fibrosis within the study group, meaning that the quality of the fat grafts was better.