A
Ana M. Valdes
Researcher at University of Nottingham
Publications - 374
Citations - 33552
Ana M. Valdes is an academic researcher from University of Nottingham. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 84, co-authored 334 publications receiving 26627 citations. Previous affiliations of Ana M. Valdes include University of California, San Francisco & Hoffmann-La Roche.
Papers
More filters
Journal ArticleDOI
Mutational processes of simple-sequence repeat loci in human populations.
TL;DR: Computer simulations were used to determine expected values of statistics that reflect frequency distributions of allele size for the two-phase model and two alternatives, the one-step and geometric models, and found that estimates of interpopulation distances from SSRs were similar to those derived from analysis of mitochondrial DNA.
Journal ArticleDOI
Obesity, cigarette smoking, and telomere length in women.
Ana M. Valdes,Toby Andrew,J. P. Gardner,Masayuki Kimura,E. Oelsner,Lynn Cherkas,Abraham Aviv,Tim D. Spector +7 more
TL;DR: It is found that telomere length decreased steadily with age at a mean rate of 27 bp per year, and the pro-ageing effects of obesity and cigarette smoking are emphasised.
Journal ArticleDOI
Role of the gut microbiota in nutrition and health
TL;DR: Ana M Valdes and colleagues discuss strategies for modulating the gut microbiota through diet and probiotics and suggest that a Mediterranean diet supplemented with probiotics can be a viable alternative to a probiotic regime.
Journal ArticleDOI
Real-time tracking of self-reported symptoms to predict potential COVID-19.
Cristina Menni,Ana M. Valdes,Ana M. Valdes,Maxim B. Freidin,Carole H. Sudre,Long H. Nguyen,David A. Drew,Sajaysurya Ganesh,Thomas Varsavsky,M. Jorge Cardoso,Julia S. El-Sayed Moustafa,Alessia Visconti,Pirro G. Hysi,Ruth C. E. Bowyer,Massimo Mangino,Massimo Mangino,Mario Falchi,Jonathan Wolf,Sebastien Ourselin,Andrew T. Chan,Claire J. Steves,Tim D. Spector +21 more
TL;DR: Analysis of data from a smartphone-based app designed for large-scale tracking of potential COVID-19 symptoms, used by over 2.5 million participants in the United Kingdom and United States, shows that loss of taste and smell sensations is predictive of potential SARS-CoV-2 infection.
Journal ArticleDOI
An atlas of genetic influences on human blood metabolites
So-Youn Shin,Eric B. Fauman,Ann-Kristin Petersen,Jan Krumsiek,Rita Santos,Jie Huang,Matthias Arnold,Idil Erte,Vincenzo Forgetta,Tsun-Po Yang,Klaudia Walter,Cristina Menni,Lu Chen,Lu Chen,Louella Vasquez,Ana M. Valdes,Ana M. Valdes,Craig L. Hyde,Vicky Wang,Daniel Ziemek,Phoebe M. Roberts,Li Xi,Elin Grundberg,Melanie Waldenberger,J. Brent Richards,Robert P. Mohney,Michael V. Milburn,Sally John,Jeff K. Trimmer,Fabian J. Theis,John P. Overington,Karsten Suhre,M. Julia Brosnan,Christian Gieger,Gabi Kastenmüller,Tim D. Spector,Nicole Soranzo +36 more
TL;DR: The most comprehensive exploration of genetic loci influencing human metabolism thus far, comprising 7,824 adult individuals from 2 European population studies, is reported, reporting genome-wide significant associations at 145 metabolic loci and their biochemical connectivity with more than 400 metabolites in human blood.