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Ana Morales
Researcher at Ohio State University
Publications - 83
Citations - 5557
Ana Morales is an academic researcher from Ohio State University. The author has contributed to research in topics: Genetic testing & Cardiomyopathy. The author has an hindex of 30, co-authored 64 publications receiving 4326 citations. Previous affiliations of Ana Morales include Brandeis University & Boston Children's Hospital.
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Journal ArticleDOI
Dilated cardiomyopathy: the complexity of a diverse genetic architecture
TL;DR: Reassessment of assumptions about the complexity of the genomic and phenomic architecture of DCM is warranted, which will require comprehensive genomic studies in much larger cohorts of rigorously phenotyped probands and family members than previously examined.
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Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline
Ray E. Hershberger,Michael M. Givertz,Carolyn Y. Ho,Daniel P. Judge,Paul F. Kantor,Kim L. McBride,Ana Morales,Matthew R.G. Taylor,Matteo Vatta,Stephanie M. Ware +9 more
TL;DR: The clinical and genetic knowledge for each cardiomyopathy varies, as did the recommendations and strength of evidence, whereas ARVD/C and LVNC are relative newcomers to the field.
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Adaptation and validation of the ACMG/AMP variant classification framework for MYH7-associated inherited cardiomyopathies: recommendations by ClinGen’s Inherited Cardiomyopathy Expert Panel
Melissa A. Kelly,Colleen Caleshu,Ana Morales,Jillian G. Buchan,Zena T. Wolf,Steven M. Harrison,Stuart A. Cook,Mitchell W Dillon,John Garcia,Eden Haverfield,Jan D. H. Jongbloed,Daniela Macaya,Arjun K. Manrai,Kate M. Orland,Gabriele Richard,Katherine Spoonamore,Matthew J Thomas,K Thomson,K Thomson,Lisa M. Vincent,Roddy Walsh,Hugh Watkins,Nicola Whiffin,Jodie Ingles,J. Peter van Tintelen,Christopher Semsarian,James S. Ware,Ray E. Hershberger,Birgit Funke,Birgit Funke +29 more
TL;DR: These adapted rules provide increased specificity for use in MYH7-associated disorders in combination with expert review and clinical judgment and serve as a stepping stone for genes and disorders with similar genetic and clinical characteristics.
Journal ArticleDOI
Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes
Jodie Ingles,Jodie Ingles,Jennifer L. Goldstein,Courtney Thaxton,Colleen Caleshu,Edward W. Corty,Stephanie B. Crowley,Kristen Dougherty,Steven M. Harrison,Jennifer McGlaughon,Laura V. Milko,Ana Morales,Bryce A. Seifert,Natasha T. Strande,K Thomson,J. Peter van Tintelen,Kathleen Wallace,Roddy Walsh,Quinn S. Wells,Nicola Whiffin,Leora Witkowski,Christopher Semsarian,Christopher Semsarian,James S. Ware,Ray E. Hershberger,Birgit Funke +25 more
TL;DR: The majority of genes previously reported as causative of HCM and commonly included in diagnostic tests have limited or no evidence of disease association, showing an established method for evaluating gene-disease associations.
Journal ArticleDOI
Arboviral Etiologies of Acute Febrile Illnesses in Western South America, 2000–2007
Brett M. Forshey,Carolina Guevara,V. Alberto Laguna-Torres,Manuel Cespedes,Jorge Vargas,Alberto Gianella,Efrain Vallejo,Cesar Madrid,Nicolas Aguayo,Eduardo Gotuzzo,Victor Suarez,Ana Morales,Luis Beingolea,Nora Reyes,Juan Perez,Monica Negrete,Claudio Rocha,Amy C. Morrison,Amy C. Morrison,Kevin L. Russell,Patrick J. Blair,James G. Olson,Tadeusz J. Kochel +22 more
TL;DR: The described arboviruses associated with acute undifferentiated febrile illness in participating clinics in four countries in South America and detailed epidemiological analysis in Iquitos, Peru are provided to provide a better understanding of the geographic range of arbaviruses in SouthAmerica.