Ana Sánchez-González

TL;DR: A single intramuscular tixagevimab–cilgavimab dose provided statistically and clinically significant protection against progression to severe COVID-19 or death versus placebo in unvaccinated individuals and safety was favourable.

TL;DR: The results support the notion that sensorimotor gating is modulated by forebrain structures and highlight the importance of the mPFC in its regulation and suggest that, apart from a hypoactive and smaller mP FC, a hyperactive NAc and smaller HPC may underlie reduced PPI levels.

TL;DR: It is found that SYP, GRIN2B, NRG1, HOMER1, DRD1 and BDNF expression is upregulated in PFC during childhood and adolescence, suggesting a more immature neurobiological endophenotype in the RHA-I strain.

TL;DR: It was found that, compared with their RLA counterparts, RHA rats show increased exploration of the novel object in the NOE test, lowered anxiety in the ZM and impaired PPI, whereas RLAs display better spatial reference learning and memory and better cognitive flexibility in a reversal task.

TL;DR: Although further behavioral and psychopharmacological work needs to be done, the present findings and previous studies allow the RHA-I rat strain to be proposed as a putative genetic rat model of differential schizophrenia-related features.