C
Cristóbal Río-Álamos
Researcher at Autonomous University of Barcelona
Publications - 25
Citations - 307
Cristóbal Río-Álamos is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: Prepulse inhibition & Medicine. The author has an hindex of 9, co-authored 19 publications receiving 205 citations. Previous affiliations of Cristóbal Río-Álamos include Austral University of Chile.
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Prepulse inhibition predicts spatial working memory performance in the inbred Roman high- and low-avoidance rats and in genetically heterogeneous NIH-HS rats: relevance for studying pre-attentive and cognitive anomalies in schizophrenia.
Ignasi Oliveras,Cristóbal Río-Álamos,Toni Cañete,Gloria Blázquez,Esther Martínez-Membrives,Osvaldo Giorgi,Maria Giuseppa Corda,Adolf Tobeña,Alberto Fernández-Teruel +8 more
TL;DR: Using genetically-selected and genetically heterogeneous rats, the present study shows, for the first time, that PPI is a positive predictor of performance in a spatial working memory task.
Journal ArticleDOI
Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume.
Carles Tapias-Espinosa,Cristóbal Río-Álamos,Ana Sánchez-González,Ignasi Oliveras,Daniel Sampedro-Viana,Maria Del Mar Castillo-Ruiz,Toni Cañete,Adolf Tobeña,Alberto Fernández-Teruel +8 more
TL;DR: The results support the notion that sensorimotor gating is modulated by forebrain structures and highlight the importance of the mPFC in its regulation and suggest that, apart from a hypoactive and smaller mP FC, a hyperactive NAc and smaller HPC may underlie reduced PPI levels.
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Neonatal handling enduringly decreases anxiety and stress responses and reduces hippocampus and amygdala volume in a genetic model of differential anxiety: Behavioral-volumetric associations in the Roman rat strains.
Cristóbal Río-Álamos,Ignasi Oliveras,Maria Antonietta Piludu,Cristina Gerbolés,Toni Cañete,Gloria Blázquez,Silvia Lope-Piedrafita,Esther Martínez-Membrives,Rafael Torrubia,Adolf Tobeña,Alberto Fernández-Teruel +10 more
TL;DR: Results showed untreated RLA rats showed higher anxiety and post-stress hormone responses, as well as greater hippocampus and amygdala volumes than untreated RHA rats, and there were positive associations between anxiety and PPI and hippocampus/amygdala volumes.
Journal ArticleDOI
Differential expression of synaptic markers regulated during neurodevelopment in a rat model of schizophrenia-like behavior
Betina Elfving,Heidi Kaastrup Müller,Ignasi Oliveras,Tina Becher Østerbøg,Cristóbal Río-Álamos,Ana Sánchez-González,Adolf Tobeña,Alberto Fernández-Teruel,Susana Aznar +8 more
TL;DR: It is found that SYP, GRIN2B, NRG1, HOMER1, DRD1 and BDNF expression is upregulated in PFC during childhood and adolescence, suggesting a more immature neurobiological endophenotype in the RHA-I strain.
Journal ArticleDOI
Volumetric brain differences between the Roman rat strains: Neonatal handling effects, sensorimotor gating and working memory.
Cristóbal Río-Álamos,Maria Antonietta Piludu,Cristina Gerbolés,Didac Barroso,Ignasi Oliveras,Ana Sánchez-González,Toni Cañete,Carles Tapias-Espinosa,Daniel Sampedro-Viana,Rafael Torrubia,Adolf Tobeña,Alberto Fernández-Teruel +11 more
TL;DR: It was found that, compared with their RLA counterparts, RHA rats show increased exploration of the novel object in the NOE test, lowered anxiety in the ZM and impaired PPI, whereas RLAs display better spatial reference learning and memory and better cognitive flexibility in a reversal task.