Anders Sönnerborg

TL;DR: EC have richer gut microbiota than untreated HIV patients, with unique bacterial signatures and a distinct metabolic profile which may contribute to control of HIV.

TL;DR: Plasma samples from 1,463 patients newly diagnosed with HIV-1 infection between 2003 and 2010 were analyzed and showed that TDR was positively associated with men who have sex with men (MSM) and subtype B infection and negatively associated with CD4 cell counts.

TL;DR: It is shown that one PI, indinavir, is present in the CSF at therapeutic concentrations, and is likely to contribute to the antiretroviral activities observed within the CNS.

TL;DR: A defect in the coexpression of perforin in granzyme A-positive CD8(+) T cells in lymphoid tissue from patients with acute HIV infection and a reduction in the perforIn-dependent nuclear translocation of granzymeA are described, suggesting that mechanisms inhibiting CTL-mediated cytotoxicity are operative in lymphoids tissue early in the course of HIV infection.

TL;DR: As LPS and HMGB1 tend to form immunologically active complexes in vitro, it is proposed that such complexes may be involved in the immune activation and pathogenesis of HIV-1 infection.