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Andrea Dunaif
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 181
Citations - 28793
Andrea Dunaif is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Polycystic ovary & Insulin resistance. The author has an hindex of 72, co-authored 173 publications receiving 26243 citations. Previous affiliations of Andrea Dunaif include Pennsylvania State University & City University of New York.
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Journal ArticleDOI
Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis.
TL;DR: Since PCOS usually has a menarchal age of onset, this makes it a particularly appropriate disorder in which to examine the ontogeny of defects in carbohydrate metabolism and for ascertaining large three-generation kindreds for positional cloning studies to identify NIDDM genes.
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Profound Peripheral Insulin Resistance, Independent of Obesity, in Polycystic Ovary Syndrome
TL;DR: PCO women have significant insulin resistance that is independent of obesity, changes in body composition, and impairment of glucose tolerance, and PCO is associated with a unique disorder of insulin action.
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Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
TL;DR: PCOS women are at significantly increased risk for IGT and type 2 diabetes mellitus at all weights and at a young age; these prevalence rates are similar in 2 different populations of PCOS women, suggesting that PCOS may be a more important risk factor than ethnicity or race for glucose intolerance in young women.
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Consensus on women's health aspects of polycystic ovary syndrome (PCOS): The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group
Bart C.J.M. Fauser,Basil C. Tarlatzis,Robert W. Rebar,Richard S. Legro,Adam H. Balen,Roger A. Lobo,Enrico Carmina,Jeffrey P. Chang,Bulent O. Yildiz,Joop S.E. Laven,Jacky Boivin,Felice Petraglia,C. N. Wijeyeratne,Robert J. Norman,Andrea Dunaif,Stephen Franks,Robert A. Wild,Daniel A. Dumesic,Kurt T. Barnhart +18 more
TL;DR: Relevant topics addressed-all dealt with in a systematic fashion-include adolescence, hirsutism and acne, contraception, menstrual cycle abnormalities, quality of life, ethnicity, pregnancy complications, long-term metabolic and cardiovascular health, and finally cancer risk.
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Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
TL;DR: In this paper, the authors summarized the state of the science since the last review in the Endocrine Reviews in 1997, and concluded that obese women with PCOS are insulin resistant, but some groups of lean affected women may have normal insulin sensitivity.