A
Andreas Barthel
Researcher at University of Düsseldorf
Publications - 17
Citations - 1473
Andreas Barthel is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Protein kinase B & Gene expression. The author has an hindex of 12, co-authored 17 publications receiving 1401 citations. Previous affiliations of Andreas Barthel include Ruhr University Bochum.
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Journal ArticleDOI
Novel concepts in insulin regulation of hepatic gluconeogenesis
Andreas Barthel,Dieter Schmoll +1 more
TL;DR: Signaling mechanisms and nuclear events that transduce the regulation of gluconeogenic enzymes and coactivator protein PGC-1 are focused on.
Journal ArticleDOI
Human adipocytes secrete mineralocorticoid-releasing factors.
Monika Ehrhart-Bornstein,V Lamounier-Zepter,A. Schraven,J. Langenbach,Holger S. Willenberg,Andreas Barthel,Hans Hauner,Samuel M. McCann,Werner A. Scherbaum,Stefan R. Bornstein +9 more
TL;DR: It is suggested that human adipocytes secrete potent mineralocorticoid-releasing factors, suggesting a direct link between obesity and hypertension.
Journal ArticleDOI
Stimulation of phosphoinositide 3-kinase/Akt signaling by copper and zinc ions: mechanisms and consequences.
Andreas Barthel,Elena A. Ostrakhovitch,Elena A. Ostrakhovitch,Philippe L. Walter,Philippe L. Walter,Andreas Kampkötter,Andreas Kampkötter,Lars-Oliver Klotz,Lars-Oliver Klotz +8 more
TL;DR: It is hypothesized that stimulation of PI3K/Akt is the molecular mechanism underlying the known insulin-mimetic effects of copper and zinc ions.
Journal ArticleDOI
Phosphoinositide 3-kinase signaling in the cellular response to oxidative stress
TL;DR: This review focuses on the molecular mechanisms involved in the regulation of PI 3-kinase signaling by oxidative stress and important players such as the glutathione and glutaredoxin system, (ii) the thioredoxin system and (iii) Ser/Thr- and Tyr phosphatases.
Journal ArticleDOI
Impaired adrenal stress response in Toll-like receptor 2-deficient mice.
Stefan R. Bornstein,Paula A. Zacharowski,Ralf R. Schumann,Andreas Barthel,Nguyen Tran,Claudia Papewalis,Valeria Rettori,Samuel M. McCann,Klaus Schulze-Osthoff,Werner A. Scherbaum,Jörg Tarnow,Kai Zacharowski +11 more
TL;DR: It is demonstrated that TLR-2 deficiency in mice is associated with reduced plasma corticosterone levels and marked cellular alterations in adrenocortical tissue, and a link between the innate immune system and the endocrine stress response is demonstrated.