A
Andreas Schröck
Researcher at University Hospital Bonn
Publications - 42
Citations - 878
Andreas Schröck is an academic researcher from University Hospital Bonn. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Carcinoma. The author has an hindex of 17, co-authored 42 publications receiving 707 citations. Previous affiliations of Andreas Schröck include University of Bonn.
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Journal ArticleDOI
Free-Circulating Methylated DNA in Blood for Diagnosis, Staging, Prognosis, and Monitoring of Head and Neck Squamous Cell Carcinoma Patients: An Observational Prospective Cohort Study
Andreas Schröck,Annette Leisse,Luka de Vos,Heidrun Gevensleben,Freya Dröge,A Franzen,Malin Wachendörfer,Friederike Schröck,J. Ellinger,Marcus Teschke,Timo Wilhelm-Buchstab,Jennifer Landsberg,Stefan Holdenrieder,Gunther Hartmann,John K. Field,Friedrich Bootz,Glen Kristiansen,Dimo Dietrich +17 more
TL;DR: Methylation testing in plasma is a powerful diagnostic tool for molecular disease staging, risk stratification, and disease monitoring, and patients with initially high biomarker levels might benefit from intensified treatment and posttherapeutic surveillance.
Journal ArticleDOI
PD-L1: a novel prognostic biomarker in head and neck squamous cell carcinoma.
Tim Müller,Martin Braun,Dimo Dietrich,Seher Aktekin,Simon Höft,Glen Kristiansen,Friederike Göke,Andreas Schröck,Johannes Brägelmann,Stefanie Andrea Erika Held,Friedrich Bootz,Peter Brossart +11 more
TL;DR: It is shown that PD-L1 expression is common in HNSCC and, more importantly, a both robust and strong prognostic biomarker, which provides hints on further application of therapies targeting the PD-1/PD-L 1 pathway in H NSCC.
Journal ArticleDOI
Expression and role of the embryonic protein SOX2 in head and neck squamous cell carcinoma
Andreas Schröck,Maike Bode,Friederike Göke,Petra M. Bareiss,Rebekka Schairer,Hui Wang,Wilko Weichert,Alina Franzen,Robert Kirsten,Tobias van Bremen,Angela Queisser,Glen Kristiansen,Lynn E. Heasley,Friedrich Bootz,Claudia Lengerke,Sven Perner +15 more
TL;DR: Functionally, SOX2 induced the expression of the antiapoptotic protein BCL-2 and enhanced resistance to apoptosis-inducing agents including cisplatin, indicatingSOX2 as a mediator of therapy resistance in human HNSCC.
Journal ArticleDOI
Fibroblast growth factor receptor 1 amplification is a common event in squamous cell carcinoma of the head and neck.
Friederike Göke,Maike Bode,Alina Franzen,Robert Kirsten,Diane Goltz,Antonia Göke,Rakesh Sharma,Diana Boehm,Wenzel Vogel,Patrick L. Wagner,Claudia Lengerke,Glen Kristiansen,Jutta Kirfel,Tobias van Bremen,Friedrich Bootz,Lynn E. Heasley,Andreas Schröck,Sven Perner +17 more
TL;DR: The data identify fibroblast growth factor receptor 1 amplification as a frequent event in primary and metastatic head and neck squamous cell carcinoma and represents a potential biomarker for more aggressive disease.
Journal ArticleDOI
Endovascular Treatment of Epistaxis: Indications, Management, and Outcome
K. Strach,Andreas Schröck,Kai Wilhelm,Susanne Greschus,Henriette J. Tschampa,Markus Möhlenbruch,Claas P. Naehle,Mark Jakob,Andreas O. H. Gerstner,Friedrich Bootz,Hans H. Schild,Horst Urbach +11 more
TL;DR: Endovascular treatment proves to be effective for prolonged and life-threatening epistaxis and is easily repeatable if the first procedure is not successful and offers a good risk–benefit profile.