A
Andrew Bentley
Researcher at University of Manchester
Publications - 97
Citations - 8863
Andrew Bentley is an academic researcher from University of Manchester. The author has contributed to research in topics: Eosinophil & Intensive care. The author has an hindex of 33, co-authored 89 publications receiving 8209 citations. Previous affiliations of Andrew Bentley include Sewanee: The University of the South & National Institutes of Health.
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Journal ArticleDOI
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
Douglas S. Robinson,Qutayba Hamid,Sun Ying,Anne Tsicopoulos,J. Barkans,Andrew Bentley,Christopher Corrigan,Stephen R. Durham,A. B. Kay +8 more
TL;DR: Atopic asthma is associated with activation in the bronchi of the interleukin-3, 4, and 5 and GM-CSF gene cluster, a pattern compatible with predominant activation of the TH2-like T-cell population.
Journal ArticleDOI
Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma
TL;DR: Cytokines produced by activated TH2-type CD4+ T cells in the airway may contribute to late asthmatic responses by mechanisms that include eosinophil accumulation.
Journal ArticleDOI
Intrapleural use of tissue plasminogen activator and DNase in pleural infection
Najib M. Rahman,Nick A Maskell,Alex West,Richard Teoh,Anthony G. Arnold,Carolyn Mackinlay,Daniel Peckham,Christopher W. H. Davies,Nabeel Ali,William Kinnear,Andrew Bentley,Brennan C Kahan,John M. Wrightson,Helen E. Davies,Clare E Hooper,Y. C. Gary Lee,Emma L. Hedley,Nicky Crosthwaite,Louise Choo,Emma J. Helm,Fergus V. Gleeson,Fergus V. Gleeson,Andrew J. Nunn,Robert J. O. Davies +23 more
TL;DR: Intrapleural t-PA-DNase therapy improved fluid drainage in patients with pleural infection and reduced the frequency of surgical referral and the duration of the hospital stay.
Journal ArticleDOI
Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness.
Andrew Bentley,Günter Menz,Chr. Storz,Douglas S. Robinson,B. Bradley,Peter K. Jeffery,Stephen R. Durham,A. B. Kay +7 more
TL;DR: Using immunohistochemistry and a panel of monoclonal antibodies, the authors have compared T-lymphocyte, eosinophil, macrophage, and neutrophil infiltration in bronchial biopsies from 10 intrinsic (nonallergic) asthmatics (IA) and seven extrinsic (all allergic) asthma (EA), with similar degrees of disease severity.
Journal ArticleDOI
Increases in Activated T Lymphocytes, Eosinophils, and Cytokine mRNA Expression for Interleukin-5 and Granulocyte/Macrophage Colony-stimulating Factor in Bronchial Biopsies after Allergen Inhalation Challenge in Atopic Asthmatics
TL;DR: The view that cytokines possibly from activated T lymphocytes may contribute to local eosinophil accumulation during allergen-induced asthma is supported.