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Andrew Kitchen
Researcher at University of Iowa
Publications - 48
Citations - 2656
Andrew Kitchen is an academic researcher from University of Iowa. The author has contributed to research in topics: Population & Genome. The author has an hindex of 23, co-authored 45 publications receiving 2300 citations. Previous affiliations of Andrew Kitchen include Pennsylvania State University & University of Florida.
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Journal ArticleDOI
Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe.
Kathryn E. Holt,Stephen Baker,François-Xavier Weill,Edward C. Holmes,Edward C. Holmes,Andrew Kitchen,Jun Yu,Vartul Sangal,Derek J. Brown,J. E. Coia,Dong Wook Kim,Dong Wook Kim,Seon Young Choi,Su Hee Kim,Wanderley Dias da Silveira,Derek Pickard,Jeremy Farrar,Julian Parkhill,Gordon Dougan,Nicholas R. Thomson +19 more
TL;DR: The phylogenetic analysis shows that the current S. sonnei population descends from a common ancestor that existed less than 500 years ago and that diversified into several distinct lineages with unique characteristics, and suggests that the majority of this diversification occurred in Europe and was followed by more recent establishment of local pathogen populations on other continents.
Journal ArticleDOI
Using Time-Structured Data to Estimate Evolutionary Rates of Double-Stranded DNA Viruses
Cadhla Firth,Andrew Kitchen,Beth Shapiro,Marc A. Suchard,Marc A. Suchard,Edward C. Holmes,Edward C. Holmes,Andrew Rambaut,Andrew Rambaut +8 more
TL;DR: The use of temporally structured sequence data within a Bayesian framework is explored to estimate the evolutionary rates for seven human dsDNA viruses, including variola virus (VARV) (the causative agent of smallpox) and herpes simplex virus-1, revealing that some ds DNA viruses may evolve at rates approaching those of RNA viruses.
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A three-stage colonization model for the peopling of the Americas.
TL;DR: A model for the peopling of the New World in which Amerind ancestors diverged from the Asian gene pool prior to 40,000 years ago and experienced a gradual population expansion as they moved into Beringia is supported.
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Bayesian phylogenetic analysis of Semitic languages identifies an Early Bronze Age origin of Semitic in the Near East
TL;DR: A relaxed linguistic clock is implemented to date language divergences and epigraphic evidence for the sampling dates of extinct Semitic languages to calibrate the rate of language evolution and statistical tests of alternative Semitic histories support an initial divergence of Akkadian from ancestral Semitic over competing hypotheses.
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Molecular evolution of the insect-specific flaviviruses
Shelley Cook,Gregory Moureau,Andrew Kitchen,Ernest A. Gould,Xavier de Lamballerie,Edward C. Holmes,Edward C. Holmes,Ralph E. Harbach +7 more
TL;DR: There is no statistical support for virus–mosquito co-divergence, suggesting that the ‘insect-specific’ flaviviruses may have undergone multiple introductions with frequent host switching, and the vast potential that exists for the study of biodiversity within a range of potential hosts and vectors is considered.