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Aneurin J. Kennerley

Researcher at University of York

Publications -  57
Citations -  1988

Aneurin J. Kennerley is an academic researcher from University of York. The author has contributed to research in topics: Medicine & Magnetic resonance imaging. The author has an hindex of 24, co-authored 51 publications receiving 1642 citations. Previous affiliations of Aneurin J. Kennerley include University of Sheffield & Hull York Medical School.

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Cortical lamina-dependent blood volume changes in human brain at 7 T

TL;DR: It is concluded that VASO offers good reproducibility, high sensitivity and lower sensitivity than GE-BOLD to changes in larger vessels, making it a valuable tool for layer-dependent fMRI studies in humans.
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Negative Blood Oxygen Level Dependence in the Rat:A Model for Investigating the Role of Suppression in Neurovascular Coupling

TL;DR: This preparation found a reliable NBR measured in rat somatosensory cortex in response to unilateral electrical whisker stimulation, which was located in deeper cortical layers relative to the positive BOLD response.
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Neurovascular coupling is brain region-dependent.

TL;DR: This study investigated neurovascular coupling in the rat using whole-brain blood oxygenation level-dependent fMRI and multi-channel electrophysiological recordings and measured the response to a sensory stimulus as it proceeded through brainstem, thalamic and cortical processing sites - the so-called whisker-to-barrel pathway.
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Fine detail of neurovascular coupling revealed by spatiotemporal analysis of the hemodynamic response to single whisker stimulation in rat barrel cortex.

TL;DR: Hemodynamics are capable of providing accurate "single-condition" maps of neural activity with a combination of high spatiotemporal resolution two-dimensional spectroscopic optical imaging, multichannel electrode recordings and cytochrome oxidase histology in the rodent whisker barrel field.
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Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting.

TL;DR: MRI scanners can not only track the location of magnetically labelled cells but also have the potential to steer them into one or more target tissues, resulting in increased tumour macrophage infiltration and reduction in tumour burden and metastasis.