Angelo Arleo

TL;DR: The spatial representation in this model of the rat hippocampus is built on-line during exploration via two processing streams and focuses on the neural pathway connecting the hippocampus to the nucleus accumbens.

TL;DR: This is the first reported case of partial functional recovery in a neurodegenerative disease after optogenetic therapy after intraocular injection of an adeno-associated viral vector encoding ChrimsonR with light stimulation via engineered goggles.

TL;DR: The authors proposed and tested the alternative hypothesis that the influence of spatial geometry on both behavioral and neuronal levels can be explained by the properties of visual features that constitute local views of the environment, and suggested that the pattern of diagonal errors observed in reorientation tasks can be understood by the analysis of sensory information processing that underlies the navigation strategy employed to solve the task.

TL;DR: Evidence is brought for the first time that a fundamental component of the capacity to rapidly reorient in a familiar environment may be brought about by updating of HD cell responses as rapidly as 80 msec after changes in the visual scene.

TL;DR: A state space representation is constructed by unsupervised Hebbian learning during exploration and a representation of the continuous two-dimensional manifold in the high-dimensional input space is found that is comparable to the representation provided by hippocampal place cells in rats.