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Angelo C. Pinto
Researcher at Federal University of Rio de Janeiro
Publications - 307
Citations - 7329
Angelo C. Pinto is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Isatin & Diterpene. The author has an hindex of 39, co-authored 307 publications receiving 6744 citations. Previous affiliations of Angelo C. Pinto include Oswaldo Cruz Foundation & University of Graz.
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Journal ArticleDOI
Anti-inflammatory and antinociceptive activities of an acid fraction of the seeds of Carpotroche brasiliensis (Raddi) (Flacourtiaceae).
Josélia A. Lima,Adriana de Sousa Oliveira,A. L. P. De Miranda,Claudia M. Rezende,Angelo C. Pinto +4 more
TL;DR: The acid fraction of the seeds of C. brasiliensis which contains cyclopentenyl fatty acids is now shown to have significant oral anti-inflammatory and peripheral antinociceptive effects.
Journal ArticleDOI
Docking of the alkaloid geissospermine into acetylcholinesterase: a natural scaffold targeting the treatment of Alzheimer’s disease
Jocley Queiroz Araújo,Josélia A. Lima,Angelo C. Pinto,Ricardo Bicca de Alencastro,Magaly Girão Albuquerque +4 more
TL;DR: Structural changes to the GSP structure are proposed, such as molecular simplification and isosteric replacement, in order to aid the design of new potential AChE inhibitors that are relevant to the treatment of Alzheimer’s disease.
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The mechanism of Sandmeyer's cyclization reaction by electrospray ionization mass spectrometry.
TL;DR: Using electrospray ionization (tandem) mass spectrometry (ESI-MS(/MS) spectrometric experiments, the Sandmeyer reaction was monitored on-line, and key intermediates were intercepted and characterized for the first time.
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Arjunolic acid in the ethanolic extract of Combretum leprosum root and its use as a potential multi-functional phytomedicine and drug for neurodegenerative disorders: anti-inflammatory and anticholinesterasic activities
Valdir Alves Facundo,Katiúscia Alexandre Rios,Ciléia M. Medeiros,Júlio Sancho Linhares Teixeira Militão,Ana L.P. Miranda,Rosângela de A. Epifanio,Meriane P. Carvalho,Aline T. Andrade,Angelo C. Pinto,Claudia M. Rezende +9 more
TL;DR: Anti-inflammatory, antinociceptive and anticholinesterasic activities were observed for roots ethanolic extract of C. leprosum and arjunolic acid, suggesting both as promising targets for the development of innovative multi-functional medicines for Alzheimer desease treatment.
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Antitumoral activity of new polyamine-naphthoquinone conjugates.
Andressa Esteves-Souza,Kelly Araujo Lucio,Andréa S. Cunha,Angelo C. Pinto,Edson L. S. Lima,Celso A. Camara,Maria D. Vargas,Cerli Rocha Gattass +7 more
TL;DR: Spermidine-1,4-naphthoquinone conjugates exhibited an increase in activity compared with the natural products and induced apoptosis of tumor cell lines by a mechanism that is mediated, at least in part, by ROS production.