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Anil Bagri
Researcher at Genentech
Publications - 37
Citations - 5209
Anil Bagri is an academic researcher from Genentech. The author has contributed to research in topics: Semaphorin & Vascular endothelial growth factor. The author has an hindex of 22, co-authored 36 publications receiving 4939 citations. Previous affiliations of Anil Bagri include University of California, San Francisco & BioMarin Pharmaceutical.
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Journal ArticleDOI
Blocking Neuropilin-1 Function Has an Additive Effect with Anti-VEGF to Inhibit Tumor Growth
Qi Pan,Yvan Chanthery,Wei-Ching Liang,Scott Stawicki,Judy Mak,Nisha Rathore,Raymond K. Tong,Joe Kowalski,Sharon Yee,Glenn Pacheco,Sarajane Ross,Zhiyong Cheng,Jennifer Le Couter,Greg Plowman,Franklin Peale,Alexander W. Koch,Yan Wu,Anil Bagri,Marc Tessier-Lavigne,Ryan J. Watts +19 more
TL;DR: It is proposed that blocking NRP1 function inhibits vascular remodeling, rendering vessels more susceptible to anti-VEGF therapy, and generated two monoclonal antibodies that bind to the Sema- and VEGF-binding domains of N RP1.
Journal ArticleDOI
Sorting of Striatal and Cortical Interneurons Regulated by Semaphorin-Neuropilin Interactions
TL;DR: Observations reveal a mechanism by which neuropilins mediate sorting of distinct neuronal populations into different brain structures, and provide evidence that, in addition to guiding axons, these receptors also control neuronal migration in the central nervous system.
Journal ArticleDOI
Neuropilin-2 Regulates the Development of Select Cranial and Sensory Nerves and Hippocampal Mossy Fiber Projections
Hang Chen,Anil Bagri,Joel Zupicich,Yimin Zou,Esther T. Stoeckli,Samuel J. Pleasure,Daniel H. Lowenstein,William C. Skarnes,Alain Chédotal,Marc Tessier-Lavigne +9 more
TL;DR: The results show that neuropilin-2 is an essential component of the Sema3F receptor and identify key roles for neuropilsen-2 in axon guidance in the PNS and CNS.
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The chemokine SDF1 regulates migration of dentate granule cells.
Anil Bagri,Theresa A. Gurney,Xiaoping He,Yong-Rui Zou,Yong-Rui Zou,Dan R. Littman,Marc Tessier-Lavigne,Marc Tessier-Lavigne,Samuel J. Pleasure +8 more
TL;DR: This study has characterized more fully the timing and route of granule cell migration during embryogenesis using in utero retroviral injections, and developed an in vitro assay that faithfully recapitulates important events in dentate gyrus morphogenesis.
Journal ArticleDOI
Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons.
Samuel J. Pleasure,Stewart A. Anderson,Robert F. Hevner,Anil Bagri,Oscar Marín,Daniel H. Lowenstein,John L.R. Rubenstein +6 more
TL;DR: Evidence is provided that, in mice, virtually all of these cells originate from progenitors in the basal telencephalon, and loss of hippocampal interneurons does not appear to have major effects on the early development of hippocampusal projection neurons nor on the pathfinding of afferrent tracts.