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Yong-Rui Zou
Researcher at Columbia University
Publications - 9
Citations - 5166
Yong-Rui Zou is an academic researcher from Columbia University. The author has contributed to research in topics: Chemokine receptor & Immunology. The author has an hindex of 7, co-authored 7 publications receiving 4972 citations. Previous affiliations of Yong-Rui Zou include New York University.
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Journal ArticleDOI
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
TL;DR: This is the first demonstration of the involvement of a G-protein-coupled chemokine receptor in neuronal cell migration and patterning in the central nervous system and may be important for designing strategies to block HIV entry into cells and for understanding mechanisms of pathogenesis in AIDS dementia.
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Requirement for RORγ in Thymocyte Survival and Lymphoid Organ Development
Zuoming Sun,Derya Unutmaz,Yong-Rui Zou,Mary Jean Sunshine,Alessandra Pierani,Susan Brenner-Morton,Reina E. Mebius,Dan R. Littman +7 more
TL;DR: It is shown that mice lacking the orphan nuclear hormone receptor RORgamma lose thymic expression of the anti-apoptotic factor Bcl-xL, which regulates the survival of CD4+8+ thymocytes and may control the temporal window during which thymocyte can undergo positive selection.
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A coordinated change in chemokine responsiveness guides plasma cell movements.
Diana C. Hargreaves,Paul L. Hyman,Theresa T. Lu,Vu N. Ngo,Afshin Bidgol,Gen Suzuki,Yong-Rui Zou,Dan R. Littman,Jason G. Cyster +8 more
TL;DR: It is demonstrated that as B cells differentiate into plasma cells they undergo a coordinated change in chemokine responsiveness that regulates their movements in secondary lymphoid organs and promotes lodgment within the bone marrow.
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The chemokine SDF1 regulates migration of dentate granule cells.
Anil Bagri,Theresa A. Gurney,Xiaoping He,Yong-Rui Zou,Yong-Rui Zou,Dan R. Littman,Marc Tessier-Lavigne,Marc Tessier-Lavigne,Samuel J. Pleasure +8 more
TL;DR: This study has characterized more fully the timing and route of granule cell migration during embryogenesis using in utero retroviral injections, and developed an in vitro assay that faithfully recapitulates important events in dentate gyrus morphogenesis.
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CXCR4 is required for the quiescence of primitive hematopoietic cells
TL;DR: It is proposed that CXCR4/CXCL12 signaling is essential to confine HSCs in the proper niche and controls their proliferation.