A
Anil Kumar Kalvala
Researcher at Florida A&M University
Publications - 26
Citations - 601
Anil Kumar Kalvala is an academic researcher from Florida A&M University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 16 publications receiving 342 citations.
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Ameliorative effect of fisetin on cisplatin-induced nephrotoxicity in rats via modulation of NF-κB activation and antioxidant defence.
Bidya Dhar Sahu,Anil Kumar Kalvala,Meghana Koneru,Jerald Mahesh Kumar,Madhusudana Kuncha,Shyam Sunder Rachamalla,Ramakrishna Sistla +6 more
TL;DR: Findings suggest that fisetin may be used as a promising adjunct candidate for cisplatin use, andimation of platinum concentration in kidney tissues revealed that f isetin treatment along with cisPlatin did not alter the cis platin uptake in kidneys tissues.
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Isoliquiritigenin reduces oxidative damage and alleviates mitochondrial impairment by SIRT1 activation in experimental diabetic neuropathy.
TL;DR: Results from this study suggest that SIRT1 activation by ILQ mimic effects of calorie restriction, that is, PGC-1α-mediated mitochondrial biogenesis, FOXO3a mediated stress resistance and AMPK mediated autophagy effects to counteract the multiple manifestations in experimental DN.
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Targeting AMPK in Diabetes and Diabetic Complications: Energy Homeostasis, Autophagy and Mitochondrial Health
Y.V. Madhavi,Nikhil Baliram Gaikwad,Veera Ganesh Yerra,Anil Kumar Kalvala,Srinivas Nanduri,Ashutosh Kumar +5 more
TL;DR: The review will explore the structure function relationships of these analogues and the prospect of targeting AMPK in diabetes and diabetic complications.
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Morin exerts neuroprotection via attenuation of ROS induced oxidative damage and neuroinflammation in experimental diabetic neuropathy.
Pragna Bachewal,Chayanika Gundu,Veera Ganesh Yerra,Anil Kumar Kalvala,Aparna Areti,Ashutosh Kumar +5 more
TL;DR: The results of this study suggest that morin has exquisite role in offering neuroprotection in experimental DN and further clinical investigation may reward in finding better alternative for the management of DN.
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Adenosine monophosphate-activated protein kinase modulation by berberine attenuates mitochondrial deficits and redox imbalance in experimental diabetic neuropathy.
TL;DR: Results from this study signify the importance of mitoprotection conferred by BRB in DN and can be used as a preliminary basis for further molecular exploration.