A
Ann E. Holtz-Morris
Researcher at Children's Hospital Oakland Research Institute
Publications - 4
Citations - 916
Ann E. Holtz-Morris is an academic researcher from Children's Hospital Oakland Research Institute. The author has contributed to research in topics: Genome & Whole genome sequencing. The author has an hindex of 4, co-authored 4 publications receiving 752 citations.
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Decoding the massive genome of loblolly pine using haploid DNA and novel assembly strategies
David B. Neale,Jill L. Wegrzyn,Kristian Stevens,Aleksey V. Zimin,Daniela Puiu,Marc W. Crepeau,Charis Cardeno,Maxim Koriabine,Ann E. Holtz-Morris,John D. Liechty,Pedro J. Martínez-García,Hans A. Vasquez-Gross,Brian Y. Lin,Jacob J. Zieve,William M. Dougherty,Sara Fuentes-Soriano,Le-Shin Wu,Don Gilbert,Guillaume Marçais,Michael Roberts,Carson Holt,Mark Yandell,John M. Davis,Katherine E. Smith,Jeffrey F. D. Dean,W. Walter Lorenz,Ross W. Whetten,Ronald R. Sederoff,Nicholas C. Wheeler,Patrick E. McGuire,Doreen Main,Carol A. Loopstra,Keithanne Mockaitis,Pieter J. deJong,James A. Yorke,Steven L. Salzberg,Charles H. Langley +36 more
TL;DR: In this paper, the authors used a whole genome shotgun approach relying on next generation sequence generated from a single haploid seed megagametophyte from a loblolly pine tree, 20-1010, that has been used in industrial forest tree breeding.
Journal ArticleDOI
Sequencing and Assembly of the 22-Gb Loblolly Pine Genome
Aleksey V. Zimin,Kristian Stevens,Marc W. Crepeau,Ann E. Holtz-Morris,Maxim Koriabine,Guillaume Marçais,Daniela Puiu,Michael Roberts,Jill L. Wegrzyn,Pieter J. de Jong,David B. Neale,Steven L. Salzberg,James A. Yorke,Charles H. Langley +13 more
TL;DR: This work employed novel strategies that allowed it to determine the loblolly pine reference genome sequence, the largest genome assembled to date, and implemented additional scaffolding methods utilizing independent genome and transcriptome assemblies to improve the contiguity and biological utility of the genome sequence.
Journal ArticleDOI
Sequence of the Sugar Pine Megagenome.
Kristian Stevens,Jill L. Wegrzyn,Aleksey V. Zimin,Daniela Puiu,Marc W. Crepeau,Charis Cardeno,Robin Paul,Daniel Gonzalez-Ibeas,Maxim Koriabine,Ann E. Holtz-Morris,Pedro J. Martínez-García,Uzay U. Sezen,Guillaume Marçais,Kathie Jermstad,Patrick E. McGuire,Carol A. Loopstra,John M. Davis,Andrew J. Eckert,Pieter J. de Jong,James A. Yorke,Steven L. Salzberg,David B. Neale,Charles H. Langley +22 more
TL;DR: New markers and gene annotation are described that are both tightly linked to Cr1 in a mapping population, and associated withCr1 in unrelated sugar pine individuals sampled throughout the species’ range, creating a solid foundation for future mapping.
Journal ArticleDOI
Insights into the loblolly pine genome: characterization of BAC and fosmid sequences
Jill L. Wegrzyn,Brian Y. Lin,Jacob J. Zieve,William M. Dougherty,Pedro J. Martínez-García,Maxim Koriabine,Ann E. Holtz-Morris,Pieter J. deJong,Marc W. Crepeau,Charles H. Langley,Daniela Puiu,Steven L. Salzberg,David B. Neale,Kristian Stevens +13 more
TL;DR: Two sets of loblolly pine genomic sequence, 103 previously assembled BACs and 90,954 newly sequenced and assembled fosmid scaffolds, were analyzed and a combination of homology and de novo methodologies were applied to identify both conserved and novel repeats.