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Nicholas C. Wheeler
Researcher at University of California, Davis
Publications - 6
Citations - 1079
Nicholas C. Wheeler is an academic researcher from University of California, Davis. The author has contributed to research in topics: Genome & Genomics. The author has an hindex of 4, co-authored 6 publications receiving 987 citations.
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Journal ArticleDOI
Decoding the massive genome of loblolly pine using haploid DNA and novel assembly strategies
David B. Neale,Jill L. Wegrzyn,Kristian Stevens,Aleksey V. Zimin,Daniela Puiu,Marc W. Crepeau,Charis Cardeno,Maxim Koriabine,Ann E. Holtz-Morris,John D. Liechty,Pedro J. Martínez-García,Hans A. Vasquez-Gross,Brian Y. Lin,Jacob J. Zieve,William M. Dougherty,Sara Fuentes-Soriano,Le-Shin Wu,Don Gilbert,Guillaume Marçais,Michael Roberts,Carson Holt,Mark Yandell,John M. Davis,Katherine E. Smith,Jeffrey F. D. Dean,W. Walter Lorenz,Ross W. Whetten,Ronald R. Sederoff,Nicholas C. Wheeler,Patrick E. McGuire,Doreen Main,Carol A. Loopstra,Keithanne Mockaitis,Pieter J. deJong,James A. Yorke,Steven L. Salzberg,Charles H. Langley +36 more
TL;DR: In this paper, the authors used a whole genome shotgun approach relying on next generation sequence generated from a single haploid seed megagametophyte from a loblolly pine tree, 20-1010, that has been used in industrial forest tree breeding.
This Provisional PDF corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon. Decoding the massive genome of loblolly pine using haploid DNA and novel assembly strategies
Jill L. Wegrzyn,Kristian Stevens,Daniela Puiu,Marc W. Crepeau,Charis Cardeno,Jacob J. Zieve,William M. Dougherty,Guillaume Marçais,Michael Roberts,Carson Holt,Mark Yandell,Katherine E. Smith,W. Walter Lorenz,Ross W. Whetten,Nicholas C. Wheeler,Patrick E. McGuire,Carol A. Loopstra,Keithanne Mockaitis,Pieter J,Steven L. Salzberg,Charles H. Langley +20 more
TL;DR: A novel strategy to sequence the genome of loblolly pine that combines unique aspects of pine reproductive biology and genome assembly methodology is developed, demonstrating a novel approach to sequencing the large and complex genomes of this important group of plants.
Journal ArticleDOI
DNA sequence variation and selection of tag single-nucleotide polymorphisms at candidate genes for drought-stress response in Pinus taeda L.
Santiago C. González-Martínez,Elhan S. Ersoz,Garth R. Brown,Nicholas C. Wheeler,David B. Neale +4 more
TL;DR: The pattern of polymorphism of 18 candidate genes for drought-stress response in Pinus taeda L., an important tree crop, is studied and a set of haplotype-tagging SNPs was selected, finding a reduction of genotyping effort of ∼30–40%, while sampling most common allelic variants, can be gained in the ongoing association studies for drought tolerance in pine.
Journal ArticleDOI
The Douglas-Fir Genome Sequence Reveals Specialization of the Photosynthetic Apparatus in Pinaceae.
David B. Neale,Patrick E. McGuire,Nicholas C. Wheeler,Kristian Stevens,Marc W. Crepeau,Charis Cardeno,Aleksey V. Zimin,Aleksey V. Zimin,Daniela Puiu,Geo Pertea,Uzay U. Sezen,Claudio Casola,Tomasz E. Koralewski,Robin Paul,Daniel Gonzalez-Ibeas,Sumaira Zaman,Richard Cronn,Mark Yandell,Carson Holt,Charles H. Langley,James A. Yorke,Steven L. Salzberg,Jill L. Wegrzyn +22 more
TL;DR: Comparative genome annotation with angiosperm species reveals gene-family expansion and contraction in Douglas-fir and other conifers which may account for some of the major morphological and physiological differences between the two major plant groups.
Book ChapterDOI
Hybridization and Introgression
TL;DR: This chapter seeks to summarize the scientific literature on hybridization and introgression in conifers with particular attention given to studies from the last quarter century.