Anna Drabik

TL;DR: In this review, problems associated with general strategies of samples preparation, and experimental demands for these processes are discussed.

TL;DR: This review provides an outline of the most important proteomic applications in the study of neurodegenerative disorders including Alzheimer's (AD), Parkinson's (PD), Huntington's (HD), and prion diseases, and also discusses advances in cancer and addiction.

TL;DR: Inspection of protein profiles, following TCA/acetone precipitation and the use of nano-scale liquid chromatography coupled to tandem mass spectrometry allowed for identification of eleven potential dependence markers, mainly cytoplasmic and mitochondrial enzymes, e.g. proteins that belong to GTPase and GST superfamilies.

TL;DR: Differences between the results and the method of optimisation for biological and non-biological samples were shown and the influence of different parameters on the quality of mass spectra was indicated.

TL;DR: Using bioinformatic peptide prediction programs, nucleolin was shown to contain multiple possible MHC class-I binding peptides in its sequence which makes nucleolin an interesting melanoma marker and target for immunodiagnostic and possibly therapeutic purposes.