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Anna Maria Wolf
Researcher at Innsbruck Medical University
Publications - 51
Citations - 5801
Anna Maria Wolf is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Cytokine & T cell. The author has an hindex of 31, co-authored 51 publications receiving 5402 citations. Previous affiliations of Anna Maria Wolf include University Hospital Bonn & Austrian Academy of Sciences.
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Increase of Regulatory T Cells in the Peripheral Blood of Cancer Patients 1
Anna Maria Wolf,Dominik Wolf,Michael Steurer,G. Gastl,Eberhard Gunsilius,Beatrix Grubeck-Loebenstein +5 more
TL;DR: Evidence is provided of an increased pool of CD4(+)CD25(+) regulatory T cells in the peripheral blood of cancer patients with potent immunosuppressive features, which should be considered for the design of immunomodulatory therapies such as dendritic cell vaccination.
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Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes
TL;DR: The presented data support the idea that adiponectin might be of critical relevance for cytokine regulation in obesity and fatty liver diseases affecting primarily macrophage functions and could represent a fundamental link between over-nutrition and an impaired inflammatory immune response.
Journal Article
Increase of regulatory T cells in the peripheral blood of cancer patients.
Anna Maria Wolf,Dominik Wolf,Michael Steurer,Guenther Gastl,Eberhard Gunsilius,Beatrix Grubeck-Loebenstein +5 more
TL;DR: In this article, the frequency of Tregs in the peripheral blood of 42 patients suffering from epithelial malignancies and from 34 healthy controls was determined by flow cytometry.
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The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.
Dominik Wolf,Anna Maria Wolf,Holger Rumpold,Heidi Fiegl,Alain G. Zeimet,Elisabeth Müller-Holzner,Martina Deibl,Guenther Gastl,Eberhard Gunsilius,Christian Marth +9 more
TL;DR: High expression levels of FoxP3 might represent a surrogate marker for an immunosuppressive milieu contributing to tumor immune escape and strategies selectively depleting Treg might improve the antitumor activity of endogenously arising tumor-reactive T cells and immunotherapies using vaccines or antibodies.
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Potential Role of Regulatory T Cells in Reversing Obesity-Linked Insulin Resistance and Diabetic Nephropathy
Kathrin Eller,Alexander H. Kirsch,Anna Maria Wolf,Sieghart Sopper,Andrea Tagwerker,Ursula Stanzl,Dominik Wolf,Wolfgang Patsch,Alexander R. Rosenkranz,Philipp Eller +9 more
TL;DR: Data suggest a potential therapeutic value of Tregs to improve insulin resistance and end organ damage in type 2 diabetes by limiting the proinflammatory milieu.