C
Christian Marth
Researcher at Innsbruck Medical University
Publications - 199
Citations - 5579
Christian Marth is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 35, co-authored 192 publications receiving 4542 citations.
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Journal ArticleDOI
The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.
Dominik Wolf,Anna Maria Wolf,Holger Rumpold,Heidi Fiegl,Alain G. Zeimet,Elisabeth Müller-Holzner,Martina Deibl,Guenther Gastl,Eberhard Gunsilius,Christian Marth +9 more
TL;DR: High expression levels of FoxP3 might represent a surrogate marker for an immunosuppressive milieu contributing to tumor immune escape and strategies selectively depleting Treg might improve the antitumor activity of endogenously arising tumor-reactive T cells and immunotherapies using vaccines or antibodies.
Journal ArticleDOI
2010 Gynecologic Cancer InterGroup (GCIG) Consensus Statement on Clinical Trials in Ovarian Cancer Report From the Fourth Ovarian Cancer Consensus Conference
Gavin Stuart,Henry C Kitchener,Monica Bacon,Andreas duBois,Michael Friedlander,Jonathan A. Ledermann,Christian Marth,Tate Thigpen,Edward L. Trimble +8 more
TL;DR: This report provides the outcomes from the Fourth Ovarian Cancer Consensus Conference.
Journal ArticleDOI
A Randomized Trial of Lymphadenectomy in Patients with Advanced Ovarian Neoplasms
Philipp Harter,Jalid Sehouli,Domenica Lorusso,Alexander Reuss,Ignace Vergote,Christian Marth,Jae Weon Kim,Francesco Raspagliesi,Björn Lampe,Giovanni Aletti,Werner Meier,David Cibula,Alexander Mustea,Sven Mahner,IB Runnebaum,B Schmalfeldt,Alexander Burges,Rainer Kimmig,Giovanni Scambia,Stefano Greggi,Felix Hilpert,Annette Hasenburg,Peter Hillemanns,Giorgio Giorda,Ingo von Leffern,Carmen Schade-Brittinger,Uwe Wagner,Andreas du Bois +27 more
TL;DR: Systematic pelvic and paraaortic lymphadenectomy in patients with advanced ovarian cancer who had undergone intraabdominal macroscopically complete resection and had normal lymph nodes both before and during surgery was not associated with longer overall or progression‐free survival and was associated with a higher incidence of postoperative complications.
Journal ArticleDOI
Methylation and Silencing of the Retinoic Acid Receptor-β2 Gene in Breast Cancer
Martin Widschwendter,Jennifer Berger,Martin Hermann,Hannes M. Müller,Albert Amberger,Michael Zeschnigk,Andreas Widschwendter,Burghard Abendstein,Alain G. Zeimet,Günter Daxenbichler,Christian Marth +10 more
TL;DR: Methylation of the RAR-beta2 gene may be an initial step in breast carcinogenesis; treatment of cancer patients with demethylating agents followed by retinoic acid may offer a new therapeutic modality.
Journal ArticleDOI
L1CAM in Early-Stage Type I Endometrial Cancer: Results of a Large Multicenter Evaluation
Alain G. Zeimet,Daniel Reimer,Monica Huszar,Boris Winterhoff,Ulla Puistola,Samira Abdel Azim,Elisabeth Müller-Holzner,Alon Ben-Arie,Léon C van Kempen,Edgar Petru,Stephan W Jahn,Yvette P. Geels,Leon F.A.G. Massuger,Frédéric Amant,Stephan Polterauer,Elisa Lappi-Blanco,Johan Bulten,Alexandra Meuter,Staci Tanouye,Peter Oppelt,Monika Stroh-Weigert,Alexander Reinthaller,Andrea Mariani,Werner O. Hackl,Michael Netzer,Uwe Schirmer,Ignace Vergote,Peter Altevogt,Christian Marth,Mina Fogel +29 more
TL;DR: L1CAM has been shown to be the best-ever published prognostic factor in FIGO stage I, type I endometrial cancers and shows clear superiority over the standardly used multifactor risk score.