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Christian Marth

Researcher at Innsbruck Medical University

Publications -  199
Citations -  5579

Christian Marth is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 35, co-authored 192 publications receiving 4542 citations.

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The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.

TL;DR: High expression levels of FoxP3 might represent a surrogate marker for an immunosuppressive milieu contributing to tumor immune escape and strategies selectively depleting Treg might improve the antitumor activity of endogenously arising tumor-reactive T cells and immunotherapies using vaccines or antibodies.
Journal ArticleDOI

Methylation and Silencing of the Retinoic Acid Receptor-β2 Gene in Breast Cancer

TL;DR: Methylation of the RAR-beta2 gene may be an initial step in breast carcinogenesis; treatment of cancer patients with demethylating agents followed by retinoic acid may offer a new therapeutic modality.