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Annagrazia Pireddu
Researcher at University of Cagliari
Publications - 7
Citations - 520
Annagrazia Pireddu is an academic researcher from University of Cagliari. The author has contributed to research in topics: Cancer & Family history. The author has an hindex of 5, co-authored 6 publications receiving 310 citations.
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Journal ArticleDOI
A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable
Alessio Cortellini,Melissa Bersanelli,Sebastiano Buti,Katia Cannita,Daniele Santini,Fabiana Perrone,Raffaele Giusti,Marcello Tiseo,Maria Michiara,Pietro Di Marino,Nicola Tinari,Michele De Tursi,Federica Zoratto,Enzo Veltri,Riccardo Marconcini,Francesco Malorgio,Marco Russano,Cecilia Anesi,Tea Zeppola,Marco Filetti,Paolo Marchetti,Andrea Botticelli,Gian Carlo Antonini Cappellini,Federica De Galitiis,Maria Giuseppa Vitale,Francesca Rastelli,Federica Pergolesi,Rossana Berardi,Silvia Rinaldi,Marianna Tudini,Rosa Rita Silva,Annagrazia Pireddu,Francesco Atzori,Rita Chiari,Biagio Ricciuti,Andrea De Giglio,Daniela Iacono,Alain Gelibter,Mario Occhipinti,Alessandro Parisi,Giampiero Porzio,Maria Concetta Fargnoli,Paolo A. Ascierto,Corrado Ficorella,Clara Natoli +44 more
TL;DR: Overweight could be considered a tumorigenic immune-dysfunction that could be effectively reversed by ICIs and BMI could be a useful predictive tool in clinical practice and a stratification factor in prospective clinical trials with ICIs.
Journal ArticleDOI
Clinical Outcomes of Patients with Advanced Cancer and Pre-Existing Autoimmune Diseases Treated with Anti-Programmed Death-1 Immunotherapy: A Real-World Transverse Study
Alessio Cortellini,Sebastiano Buti,Daniele Santini,Fabiana Perrone,Raffaele Giusti,Marcello Tiseo,Melissa Bersanelli,Maria Michiara,Antonino Grassadonia,Davide Brocco,Nicola Tinari,Michele De Tursi,Federica Zoratto,Enzo Veltri,Riccardo Marconcini,Francesco Malorgio,Carlo Garufi,Marco Russano,Cecilia Anesi,Tea Zeppola,Marco Filetti,Paolo Marchetti,Andrea Botticelli,Gian Carlo Antonini Cappellini,Federica De Galitiis,Maria Giuseppa Vitale,Roberto Sabbatini,Sergio Bracarda,Rossana Berardi,Silvia Rinaldi,Marianna Tudini,Rosa Rita Silva,Annagrazia Pireddu,Francesco Atzori,Rita Chiari,Biagio Ricciuti,Daniela Iacono,Maria Rita Migliorino,Antonio Rossi,Giampiero Porzio,Katia Cannita,Valeria Ciciarelli,Maria Concetta Fargnoli,Paolo A. Ascierto,Corrado Ficorella +44 more
TL;DR: The finding of a greater incidence of irAEs among female patients ranks among the "hot topics" in gender-related differences in immuno-oncology.
Journal ArticleDOI
Correlations Between the Immune-related Adverse Events Spectrum and Efficacy of Anti-PD1 Immunotherapy in NSCLC Patients
Alessio Cortellini,Rita Chiari,Biagio Ricciuti,Giulio Metro,Fabiana Perrone,Marcello Tiseo,Melissa Bersanelli,Paola Bordi,Daniele Santini,Raffaele Giusti,Antonino Grassadonia,Pietro Di Marino,N. Tinari,Michele De Tursi,Federica Zoratto,Enzo Veltri,Francesco Malorgio,Carlo Garufi,Marco Russano,Cecilia Anesi,Tea Zeppola,Marco Filetti,Paolo Marchetti,Rossana Berardi,Silvia Rinaldi,Marianna Tudini,Rosa Rita Silva,Annagrazia Pireddu,Francesco Atzori,Daniela Iacono,Maria Rita Migliorino,Giampiero Porzio,Katia Cannita,Corrado Ficorella,Sebastiano Buti +34 more
TL;DR: It is confirmed that irAEs are concordantly related to higher ORR, longer PFS, and longer OS with anti-PD-1 immunotherapy in patients with NSCLC.
Journal ArticleDOI
INfluenza Vaccine Indication during therapy with Immune checkpoint inhibitors: A transversal challenge. the INVIDIa study
Melissa Bersanelli,Diana Giannarelli,Paola Castrignanò,Giuseppe Fornarini,Stefano Panni,Francesca Mazzoni,Marcello Tiseo,Sabrina Rossetti,Elisabetta Gambale,Ernesto Rossi,Anselmo Papa,Alessio Cortellini,Cristian Lolli,Raffaele Ratta,Maria Michiara,Michele Milella,Emmanuele De Luca,Mariella Sorarù,Claudia Mucciarini,Francesco Atzori,Giuseppe Luigi Banna,Leonardo La Torre,Maria Giuseppa Vitale,Francesco Massari,Sara Elena Rebuzzi,Gaetano Facchini,Giovanni Schinzari,Silverio Tomao,Simona Bui,Vanja Vaccaro,Giuseppe Procopio,Ugo De Giorgi,Matteo Santoni,Corrado Ficorella,Roberto Sabbatini,Antonio Maestri,Clara Natoli,Michele De Tursi,Massimo Di Maio,Elena Rapacchi,Annagrazia Pireddu,Teodoro Sava,Helga Lipari,Francesca Comito,Elena Verzoni,Francesco Leonardi,Sebastiano Buti +46 more
TL;DR: Although influenza vaccine may be clinically ineffective in advanced cancer patients receiving CKI, it seems not to negatively impact the efficacy of anticancer therapy.
Journal ArticleDOI
Family history of cancer as surrogate predictor for immunotherapy with anti-PD1/PD-L1 agents: preliminary report of the FAMI-L1 study.
Alessio Cortellini,Melissa Bersanelli,Sebastiano Buti,Elisabetta Gambale,Francesco Atzori,Federica Zoratto,Alessandro Parisi,Davide Brocco,Annagrazia Pireddu,Katia Cannita,Daniela Iacono,Maria Rita Migliorino,Teresa Gamucci,Michele De Tursi,Tina Sidoni,Marcello Tiseo,Maria Michiara,Anselmo Papa,Gesuino Angius,Silverio Tomao,Maria Concetta Fargnoli,Clara Natoli,Corrado Ficorella +22 more
TL;DR: This pilot study seems to individuate easily available patient's features as possible predictive surrogates of clinical benefit for anti-PD-1/PD-L1 treatments, and need to be confirmed with a greater sample size, in prospective trials with immunotherapy.