Annalisa Masi

TL;DR: This review focuses on fatty acid biomarkers with two examples of recent lipidomic research and health applications: monounsaturated fatty acids and the analytical challenge offered by hexadecenoic fatty acids (C16:1); and the cohort of 10 fatty acids in phospholipids of red blood cell membranes and its connections to metabolic and nutritional status in healthy and diseased subjects.

TL;DR: The locally impaired stacking interaction energies correlate with relative NER incision efficiencies, and explain these results on a structural basis in terms of differences in dynamic perturbations of the DNA backbone imposed by the R and S covalent 5′,8 bonds.

TL;DR: It is proved that Doxorubsicin and Sabarubicin bind to the human telomeric sequence, 5'-d[GGG(TTAGGG)(3)]-3' (21-mer), assuming a G-quadruplex structure in the presence of K(+).

TL;DR: This review describes the main recent achievements in the preparation of the cPu molecular library for analytical and DNA synthesis applications for the studies of the enzymatic recognition and repair mechanisms, their impact on transcription and genetic instability, and quantitative determination of the levels of lesions in various types of cells and animal model systems.

TL;DR: This study indicates that accumulation of cdPus in the human genome can lead to TNR instability via a unique lesion bypass by pol β.