Anne Krümpel

TL;DR: The present meta-analysis indicates that detection of IT is clinically meaningful in children with, or at risk for, VTE and underscores the importance of pediatric thrombophilia screening programs.

TL;DR: A review of literature published in any language since 1980 on LMWH in neonates, infants and children found that neonates and younger infants require higher LMWH doses than older children to achieve the targeted anti‐Xa levels, due to an increased extra vascular clearance.

TL;DR: Assessment of health‐related quality of life in children and adolescents who survived a first stroke episode by self-assessment and parent/proxy‐assessment is conducted.

TL;DR: Given the high absolute risk of VTE in relatives with protein C, protein S, and antithrombin deficiency, it is suggested screening for these forms of hereditary thrombophilia in children with VTE and their relatives.

TL;DR: The present systematic review suggests that use of LMWH in children as primary prophylaxis and in treatment of symptomatic thrombosis is effective and safe, however, properly designed randomized controlled trials are needed.