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Anne M. Danks
Publications - 2
Citations - 239
Anne M. Danks is an academic researcher. The author has contributed to research in topics: Genetically modified mouse & Receptor. The author has an hindex of 1, co-authored 2 publications receiving 226 citations.
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Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease
Maria Z. Kounnas,Anne M. Danks,Soan Cheng,Curtis M. Tyree,Elizabeth J. Ackerman,Xulun Zhang,Kwangwook Ahn,Phuong T. Nguyen,Dan Comer,Long Mao,Chengzhi Yu,David P. M. Pleynet,Paul J. Digregorio,Gonul Velicelebi,Kenneth A. Stauderman,William T. Comer,William C. Mobley,Yue-Ming Li,Sangram S. Sisodia,Rudolph E. Tanzi,Steven L. Wagner +20 more
TL;DR: Over 1200 novel gamma-secretase modulator compounds were synthesized that reduced Abeta(42) levels without inhibiting epsilon-site cleavage of APP and Notch, the generation of the APP and notch intracellular domains, respectively.