A
Anne M.J. Verstegen
Researcher at Beth Israel Deaconess Medical Center
Publications - 16
Citations - 1156
Anne M.J. Verstegen is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Kisspeptin & Hypothalamus. The author has an hindex of 10, co-authored 16 publications receiving 837 citations. Previous affiliations of Anne M.J. Verstegen include Harvard University & Istituto Italiano di Tecnologia.
Papers
More filters
Journal ArticleDOI
A molecular census of arcuate hypothalamus and median eminence cell types
John N. Campbell,Evan Z. Macosko,Henning Fenselau,Tune H. Pers,Tune H. Pers,Anna Lyubetskaya,Danielle Tenen,Melissa Goldman,Melissa Goldman,Anne M.J. Verstegen,Jon M. Resch,Steven A. McCarroll,Evan D. Rosen,Evan D. Rosen,Bradford B. Lowell,Bradford B. Lowell,Linus T.-Y. Tsai +16 more
TL;DR: Drop-seq is extended to detect dynamic expression changes across relevant physiological perturbations, revealing cell type–specific responses to energy status, including distinct responses in AgRP and POMC neuron subtypes.
Journal ArticleDOI
A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH.
Henning Fenselau,John N. Campbell,Anne M.J. Verstegen,Joseph C. Madara,Jie Xu,Bhavik P. Shah,Jon M. Resch,Zongfang Yang,Yael Mandelblat-Cerf,Yoav Livneh,Bradford B. Lowell,Bradford B. Lowell +11 more
TL;DR: It is shown that glutamate-releasing ARC neurons expressing oxytocin receptor, unlike ARCPOMC neurons, rapidly cause satiety when chemo- or optogenetically manipulated, and its modulation by α-MSH provides insight into regulation of hunger and satiety.
Journal ArticleDOI
Phosphorylation of Synapsin I by Cyclin-Dependent Kinase-5 Sets the Ratio between the Resting and Recycling Pools of Synaptic Vesicles at Hippocampal Synapses
Anne M.J. Verstegen,Erica Tagliatti,Gabriele Lignani,Antonella Marte,Tamar Stolero,Merav Atias,Anna Corradi,Flavia Valtorta,Daniel Gitler,Franco Onofri,Anna Fassio,Fabio Benfenati +11 more
TL;DR: Cdk5 phosphorylation of SynI fine tunes the recruitment of SVs to the active recycling pool and contributes to the Cdk5-mediated homeostatic responses, demonstrating that SynI is necessary and sufficient for achieving the effects of the kinase on SV trafficking.
Journal ArticleDOI
PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse.
Rachel A. Ross,Silvia Leon,Joseph C. Madara,Joseph C. Madara,Danielle Schafer,Chrysanthi Fergani,Chrysanthi Fergani,Caroline A Maguire,Anne M.J. Verstegen,Anne M.J. Verstegen,Emily Brengle,Emily Brengle,Dong Kong,Allan E. Herbison,Ursula B. Kaiser,Ursula B. Kaiser,Bradford B. Lowell,Bradford B. Lowell,Víctor M. Navarro,Víctor M. Navarro +19 more
TL;DR: It is demonstrated that PACAP-expressing neurons of the ventral premamillary nucleus of the hypothalamus (PMVPACAP) project to, and make direct contact with, kisspeptin neurons in the arcuate and AVPV/PeN nuclei and a subset of these neurons respond to PACAP exposure.
Journal ArticleDOI
Barrington's nucleus: Neuroanatomic landscape of the mouse “pontine micturition center”
Anne M.J. Verstegen,Anne M.J. Verstegen,Veronique G.J.M. VanderHorst,Veronique G.J.M. VanderHorst,Paul A. Gray,Mark L. Zeidel,Mark L. Zeidel,Joel C. Geerling,Joel C. Geerling +8 more
TL;DR: Barrington's nucleus (Bar) is thought to contain neurons that trigger voiding and thereby function as the "pontine micturition center" in mice.