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Anne T. Saber
Researcher at National Institute of Occupational Health
Publications - 84
Citations - 3831
Anne T. Saber is an academic researcher from National Institute of Occupational Health. The author has contributed to research in topics: Bronchoalveolar lavage & Genotoxicity. The author has an hindex of 34, co-authored 76 publications receiving 3202 citations.
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Journal ArticleDOI
Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver
Julie A. Bourdon,Anne T. Saber,Nicklas Raun Jacobsen,Keld Alstrup Jensen,Anne Mette Madsen,Jacob Stuart Lamson,Håkan Wallin,Peter Møller,Steffen Loft,Carole L. Yauk,Ulla Vogel +10 more
TL;DR: The results demonstrate that CBNPs may cause genotoxicity both in the primary exposed tissue, lung and BAL cells, and in a secondary tissue, the liver.
Journal ArticleDOI
MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs.
Sarah S. Poulsen,Anne T. Saber,Andrew Williams,Ole Andersen,Carsten Købler,Rambabu Atluri,Maria E. Pozzebon,Stefano Pozzi Mucelli,Monica Simion,David Rickerby,Alicja Mortensen,Petra Jackson,Zdenka O. Kyjovska,Kristian Mølhave,Nicklas Raun Jacobsen,Keld Alstrup Jensen,Carole L. Yauk,Håkan Wallin,Sabina Halappanavar,Ulla Vogel +19 more
TL;DR: The results indicate that the extent of change at the molecular level during early response phases following an acute exposure is greater in mice exposed to CNT(Large), which may eventually lead to the different responses observed at day 28.
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ITS-NANO - Prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy
Vicki Stone,Stefano Pozzi-Mucelli,Lang Tran,Karin Aschberger,Stefania Sabella,Ulla Vogel,Craig A Poland,Dominique Balharry,Teresa F. Fernandes,Stefania Gottardo,Steven M. Hankin,Mark G. J. Hartl,Nanna B. Hartmann,Danial Hristozov,Kerstin Hund-Rinke,Helinor Jane Johnston,Antonio Marcomini,Oliver Panzer,Davide Roncato,Anne T. Saber,Håkan Wallin,Janeck J. Scott-Fordsmand +21 more
TL;DR: ITS-NANO has delivered a detailed, stakeholder driven and flexible research prioritisation tool, which identifies specific research needs, suggests connections between areas, and frames this in a time-perspective.
Journal ArticleDOI
Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers.
Anne T. Saber,Keld Alstrup Jensen,Nicklas Raun Jacobsen,Renie K. Birkedal,Lone Mikkelsen,Peter Møller,Steffen Loft,Håkan Wallin,Ulla Vogel +8 more
TL;DR: The uncoated titanium dioxide was not DNA damaging by the comet assay 24 h after exposure despite being highly inflammogenic, suggesting that inflammation is not a prerequisite to DNA damage in titanium dioxide-based products.
Journal ArticleDOI
Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells.
Nicklas Raun Jacobsen,Anne T. Saber,Paul D. White,Peter Møller,Giulio Pojana,Ulla Vogel,Steffen Loft,John D. Gingerich,Lynda M. Soper,George R. Douglas,Håkan Wallin +10 more
TL;DR: Carbon black and quartz are relatively inert solid particulate materials that are carcinogenic in laboratory animals as mentioned in this paper, and there are few data on mammalian mutagenesis, however, the results do not necessarily imply that other carbonaceous nano materials are genotoxic.