A
Anneli Cooper
Researcher at University of Glasgow
Publications - 37
Citations - 1175
Anneli Cooper is an academic researcher from University of Glasgow. The author has contributed to research in topics: Trypanosoma brucei & African trypanosomiasis. The author has an hindex of 16, co-authored 33 publications receiving 954 citations. Previous affiliations of Anneli Cooper include Australian Antarctic Division & Life Sciences Institute.
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Journal ArticleDOI
The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes
Paul Capewell,Christelle Cren-Travaillé,Francesco Marchesi,Pamela Johnston,Caroline Clucas,Robert A. Benson,Taylor-Anne Gorman,Estefania Calvo-Alvarez,Aline Crouzols,Grégory Jouvion,Vincent Jamonneau,William Weir,M. Lynn Stevenson,Kerry O'Neill,Anneli Cooper,Nono-raymond Kuispond Swar,Bruno Bucheton,Dieudonné Mumba Ngoyi,Paul Garside,Brice Rotureau,Annette MacLeod +20 more
TL;DR: It is shown that substantial quantities of trypanosomes exist within the skin following experimental infection, which can be transmitted to the tsetse vector, even in the absence of detectable parasitaemia.
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The Mechanism of Superantigen-Mediated Toxic Shock: Not a Simple Th1 Cytokine Storm
TL;DR: The results demonstrate unequivocally that TCRαβ T cells are critical for lethality in toxic shock but it is the early TNF-α response and not the later cytokine surge that mediates lethal shock.
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APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis
Anneli Cooper,Hamidou Ilboudo,V Pius Alibu,V Pius Alibu,Sophie Ravel,John Enyaru,John Enyaru,William Weir,Harry Noyes,Harry Noyes,Harry Noyes,Paul Capewell,Mamadou Camara,Jacqueline Milet,Vincent Jamonneau,Vincent Jamonneau,Oumou Camara,Enock Matovu,Bruno Bucheton,Bruno Bucheton,Annette MacLeod,Annette MacLeod +21 more
TL;DR: Both forms of human African trypanosomiasis are implicate in the selection and persistence of otherwise detrimental APOL1 kidney disease variants.
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Population genomics reveals the origin and asexual evolution of human infective trypanosomes
William Weir,Paul Capewell,Bernardo J. Foth,Caroline Clucas,Andrew W. Pountain,Pieter C. Steketee,Nicola Veitch,Mathurin Koffi,Thierry De Meeûs,Jacques Kaboré,Mamadou Camara,Anneli Cooper,Andy Tait,Vincent Jamonneau,Bruno Bucheton,Matthew Berriman,Annette MacLeod +16 more
TL;DR: The Meselson effect is demonstrated for the first time at the genome-wide level in any organism and large regions of loss of heterozygosity are shown, which are hypothesised to be a short-term compensatory mechanism for counteracting deleterious mutations.
Journal ArticleDOI
Allelic segregation and independent assortment in T-brucei crosses: Proof that the genetic system is Mendelian and involves meiosis
Annette MacLeod,Alison Tweedie,Sarah McLellan,Sonya Taylor,Anneli Cooper,Lindsay Sweeney,C. Michael R. Turner,Andy Tait +7 more
TL;DR: Data provided provide statistically robust proof that the genetic system is Mendelian and that meiosis occurs and support the occurrence of meiosis to form haploid gametes that then fuse to form the diploid progeny in a single round of mating.