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Anthony Falluel-Morel

Researcher at University of Rouen

Publications -  38
Citations -  2832

Anthony Falluel-Morel is an academic researcher from University of Rouen. The author has contributed to research in topics: Cerebellum & Granule cell. The author has an hindex of 23, co-authored 38 publications receiving 2577 citations. Previous affiliations of Anthony Falluel-Morel include European Institute & French Institute of Health and Medical Research.

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Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery

TL;DR: The present report reviews the current knowledge concerning the pleiotropic actions of PACAP and discusses its possible use for future therapeutic applications.
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Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain.

TL;DR: Triggering ERK signaling in tanycytes with EGF reestablishes leptin transport, elicits MBH neuron activation and energy expenditure in obese animals, and accelerates the restoration of leptin sensitivity upon the return to a normal-fat diet.
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Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death

TL;DR: It is reported that pituitary adenylate cyclase-activating polypeptide (PACAP) can prevent the deleterious effect of ethanol on neuronal precursors and is a potent protective agent against ethanol-induced neuronal cell death.
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Developmental mercury exposure elicits acute hippocampal cell death, reductions in neurogenesis, and severe learning deficits during puberty

TL;DR: It is indicated that exposure to one dose of MeHg during the perinatal period acutely induces apoptotic cell death, which results in later deficits in hippocampal structure and function.
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Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells.

TL;DR: The present study reveals that C2‐ceramide and PACAP exert opposite effects on Bax and Bcl‐2 through, respectively, JNK‐ and ERK‐dependent mechanisms, and indicates that the mitochondrial pathway plays a pivotal role in the pro‐ and anti‐apoptotic effects of C2 •ceramide • PACAP.