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Elisabeth Chachaty

Researcher at Institut Gustave Roussy

Publications -  69
Citations -  7124

Elisabeth Chachaty is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Antibiotics & Moxifloxacin. The author has an hindex of 26, co-authored 69 publications receiving 5459 citations. Previous affiliations of Elisabeth Chachaty include Université Paris-Saclay & University of Paris-Sud.

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Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

TL;DR: A key role is revealed for Bacteroidales in the immunostimulatory effects of CTLA-4 blockade, which is found to depend on distinct Bacteroides species in mice and patients.
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The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

TL;DR: It is demonstrated that cyclophosphamide alters the composition of microbiota in the small intestine and induces the translocation of selected species of Gram-positive bacteria into secondary lymphoid organs, which suggests that the gut microbiota help shape the anticancer immune response.
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Trends in human fecal carriage of extended-spectrum β-lactamases in the community: toward the globalization of CTX-M.

TL;DR: It is suggested that CTX-M carriage is evolving toward a global pandemic but is still insufficiently described, and only a better knowledge of its dynamics and biology will lead to further development of appropriate control measures.
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Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

TL;DR: Enterococcus hirae and B. intestinihominis represent valuable "oncomicrobiotics" ameliorating the efficacy of the most common alkylating immunomodulatory compound CTX, and selectively predicted longer progression-free survival in advanced lung and ovarian cancer patients treated with chemo-immunotherapy.
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Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study.

Caroline Charlier, +1778 more
TL;DR: Evidence of a significantly reduced survival in patients with neurolisteriosis treated with adjunctive dexamethasone is found, and the time window for fetal losses is determined, which is higher than reported elsewhere.