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Antonella Capozzi
Researcher at Sapienza University of Rome
Publications - 60
Citations - 1245
Antonella Capozzi is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Antiphospholipid syndrome & Lipid raft. The author has an hindex of 16, co-authored 51 publications receiving 959 citations.
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Journal ArticleDOI
A New 4-phenyl-1,8-naphthyridine Derivative Affects Carcinoma Cell Proliferation by Impairing Cell Cycle Progression and Inducing Apoptosis
Antonella Capozzi,Elisabetta Mantuano,Paola Matarrese,Giuseppe Saccomanni,Clementina Manera,Vincenzo Mattei,Lucrezia Gambardella,Walter Malorni,Maurizio Sorice,Roberta Misasi +9 more
TL;DR: It is hypothesized that the dual effects of naphthyridine derivative on cell cycle and mitotic spindle were obtained at very low concentrations, i.e. micromolar concentrations, and could represent a new promising tool in the control of cancer cell proliferation.
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Oxidized Human Beta2-Glycoprotein I: Its Impact on Innate Immune Cells
TL;DR: The role of oxidative stress in β2-GPI-mediated immune response is described in the light of research experience and of relevant literature emerging in the field.
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LRP6 mediated signal transduction pathway triggered by tissue plasminogen activator acts through lipid rafts in neuroblastoma cells.
Gloria Riitano,Valeria Manganelli,Antonella Capozzi,Vincenzo Mattei,Serena Recalchi,Stefano Martellucci,Agostina Longo,Roberta Misasi,Tina Garofalo,Maurizio Sorice +9 more
TL;DR: It is demonstrated that LRP6 mediated signal transduction pathway triggered by tPA acts through lipid rafts in neuroblastoma cells, suggesting that cyclodextrins, and potentially other drugs, such as statins, may represent an useful tool.
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"Non-criteria antiphospholipid antibodies": bridging the gap between seropositive and seronegative Antiphospholipid Syndrome.
Simona Truglia,S. Mancuso,Antonella Capozzi,Serena Recalchi,Gloria Riitano,Agostina Longo,Sara De Carolis,Francesca Romana Spinelli,Cristiano Alessandri,Fulvia Ceccarelli,Caterina De Carolis,Roberta Misasi,Maurizio Sorice,Fabrizio Conti +13 more
TL;DR: In this article, the prevalence of noncriteria anti-phospholipid (aPL) antibodies and their role in the diagnosis, treatment and prognosis in a cohort of patients with clinical features consistent with a diagnosis of antiphospholine syndrome (APS), but persistently negative for criteria aPL-anti-cardiolipin antibodies (aCL), anti-β2-glycoprotein I antibodies (α-2-GPI), and lupus anticoagulant (LA) -named seronegative APS (SN-APS
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Acute longitudinal myelitis following Cryptococcus laurentii pneumonia in a patient with systemic lupus erythematosus
Fabrizio Conti,Francesca Romana Spinelli,Serena Colafrancesco,Simona Truglia,Fulvia Ceccarelli,F Fattapposta,Maurizio Sorice,Antonella Capozzi,G Ferretti,Roberta Priori,F. Martinelli,Carmelo Pirone,Cristiano Alessandri,Guido Valesini +13 more
TL;DR: This is the first case of Cryptococcus laurentii infection and ALM in a patient with SLE who later developed a seronegative APS and the patient was treated with antimycotics, high doses of glucocorticoids and intravenous immunoglobulins with a significant clinical and radiological improvement.