Antonino Crinò

TL;DR: Plasma somatomedin‐C (SM‐C) levels were significantly higher in obese than control children, and were negatively correlated with the peak plasma GH levels, implying that it may be due to the feedback inhibition operated by the elevated plasma levels of SM‐C.

TL;DR: It is suggested that the acronym PNDM be replaced with the more comprehensive permanent diabetes mellitus of infancy (PDMI), linking it to the gene product (e.g., GCK‐PDMI, KCNJ11‐ PDMI) to avoid confusion between patients with early‐onset, autoimmune type 1 diabetes.

TL;DR: The main novelties deriving from the Italian experience lie in the definition, screening of the cardiometabolic and hepatic risk factors and the endorsement of a staged approach to treatment.

TL;DR: Overall, there was no increase in number of deaths during GH treatment, suggesting that GH administration in patients with PWS, as a group, does not increase the risk of death.

TL;DR: Normal-weight and overweight participants were less involved in bullying than obese participants; severely obese males were more involved in the double role of bully and victim and weight status categories were not directly related to bullying behaviour.