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Antonio Solinas
Researcher at University of Sassari
Publications - 46
Citations - 3520
Antonio Solinas is an academic researcher from University of Sassari. The author has contributed to research in topics: Cirrhosis & Hepatocellular carcinoma. The author has an hindex of 23, co-authored 46 publications receiving 3342 citations. Previous affiliations of Antonio Solinas include Royal Free Hospital & University of Verona.
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Journal ArticleDOI
Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients
Giovanna Fattovich,G. Giustina,F Degos,F Tremolada,G. Diodati,Piero Luigi Almasio,Frederik Nevens,Antonio Solinas,D. Mura,J T Brouwer,H Thomas,C. Njapoum,C Casarin,Bonetti P,P. Fuschi,J. Basho,A. Tocco,A. Bhalla,R. Galassini,Franco Noventa,S W Schalm,G Realdi +21 more
TL;DR: In this cohort of patients, life expectancy is relatively long, in agreement with the morbidity data showing a slowly progressive disease.
Journal ArticleDOI
Occurrence of hepatocellular carcinoma and decompensation in Western European patients with cirrhosis type B
Giovanna Fattovich,Giuliano Giustina,Solko W. Schalm,Stephanos J. Hadziyannis,José María Sánchez-Tapias,Piero Luigi Almasio,Erik Christensen,Kim Krogsgaard,Françoise Degos,Miguel Carneiro de Moura,Antonio Solinas,Franco Noventa,Giuseppe Realdi +12 more
TL;DR: High proportion of patients with HBsAg‐positive compensated cirrhosis do not experience worsening of their condition for several years, but once decompensation occurs life expectancy is poor, and European, white patients with compensated Cirrhosis type B are at consistent risk for HCC.
Journal ArticleDOI
Effectiveness of interferon alfa on incidence of hepatocellular carcinoma and decompensation in cirrhosis type C
Giovanna Fattovich,Giuliano Giustina,Françoise Degos,G. Diodati,Federico Tremolada,Frederik Nevens,Piero Luigi Almasio,Antonio Solinas,Johannes T. Brouwer,Howard C. Thomas,Giuseppe Realdi,Roberto Corrocher,Solko W. Schalm +12 more
TL;DR: This analysis did not detect any significant benefit of interferon alfa on morbidity in patients with compensated cirrhosis type C, although it suggests a reduction in complications of Cirrhosis for those with a sustained response to therapy, and it indicates the need for better therapies.
Journal ArticleDOI
Delayed clearance of serum HBsAg in compensated cirrhosis B: relation to interferon alpha therapy and disease prognosis. European Concerted Action on Viral Hepatitis (EUROHEP)
Giovanna Fattovich,Giuliano Giustina,José María Sánchez-Tapias,Carlos Quero,A. Mas,Pia Grazia Olivotto,Antonio Solinas,Piero Luigi Almasio,Stephanos J. Hadziyannis,Françoise Degos,de Moura Mc,Kim Krogsgaard,M. Pantalena,Giuseppe Realdi,Roberto Corrocher,Solko W. Schalm +15 more
TL;DR: The incidence of HBsAg loss is about 0.8% in cirrhosis type B and prognostic factors for clearance are initial HBeAg positivity and therapy with alpha interferon.
Journal ArticleDOI
Long-term follow-up of patients with chronic hepatitis C treated with different doses of interferon-α2b
Giorgio Maria Saracco,Floriano Rosina,Maria Lorena Abate,Livio Chiandussi,Vittorio Gallo,Elena Cerutti,Angelo Di Napoli,Antonio Solinas,A. Deplano,A. Tocco,P.A. Cossu,David Y. Chien,George Kuo,Alan Polito,Amy J. Weiner,Michael Houghton,Giorgio Verme,Ferruccio Bonino,Mario Rizzetto +18 more
TL;DR: Eighty patients with chronic hepatitis C who completed a previously reported randomized controlled trial on the efficacy of interferon‐α2b were followed up for at least 36 mo after therapy discontinuation, finding sex, age, hepatitis C virus antibody status, source of infection and pretreatment levels of ALT were not predictive of long‐term response.