Anzhelika Butenko

TL;DR: This review covers recent advances in the study of insect trypanosomatids, highlighting their diversity as well as genetic, morphological and biochemical complexity, which, until recently, was underappreciated.

TL;DR: It is demonstrated that L. seymouri is well adapted for the environment of the warm-blooded host and remains a predominantly monoxenous species not capable of infecting vertebrate cells under normal conditions.

TL;DR: A high-quality genome for Leptomonas pyrrhocoris, which is closely related to the dixenous genus Leishmania, is presented and several additional proteins potentially involved in virulence are identified, including SpoU methylase and U3 small nucleolar ribonucleoprotein IMP3.

TL;DR: The transition from a free‐living to a parasitic life style has resulted in the loss of approximately 50% of protein‐coding genes and a dramatic reduction in genome size, but B. saltans and trypanosomatids still share a significant number of common metabolic traits.

TL;DR: A broad survey of RNA viruses within trypanosomatids revealed several previously unidentified viral taxa including one designated “Leishbunyaviridae” and a highly divergent virus termed ”Leptomonas pyrrhocoris ostravirus 1”, which shed important insights on the emergence of viruses within an important trypanOSomatid clade relevant to human disease.