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Andrew P. Jackson
Researcher at University of Liverpool
Publications - 49
Citations - 2930
Andrew P. Jackson is an academic researcher from University of Liverpool. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 28, co-authored 49 publications receiving 2546 citations. Previous affiliations of Andrew P. Jackson include University of Oxford & Wellcome Trust Sanger Institute.
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Journal ArticleDOI
The genome of the simian and human malaria parasite Plasmodium knowlesi
Arnab Pain,Ulrike Böhme,Andrew Berry,Karen Mungall,Robert D. Finn,Andrew P. Jackson,Tobias Mourier,Jaina Mistry,Erica M. Pasini,Martin Aslett,S. Balasubrammaniam,Karsten M. Borgwardt,Karen Brooks,Celine Carret,Tim Carver,Inna Cherevach,Tracey Chillingworth,Taane G. Clark,Taane G. Clark,Mary R. Galinski,Neil Hall,D. Harper,David Harris,Heidi Hauser,Al Ivens,Christoph S. Janssen,Thomas M. Keane,Natasha Larke,Stacey A. Lapp,Matthias Marti,Sharon Moule,Irmtraud M. Meyer,Douglas Ormond,Nicholas S. Peters,Mandy Sanders,S. Sanders,Tobias Sargeant,Tobias Sargeant,Mark Simmonds,Frances Smith,R. Squares,Scott Thurston,Adrian Tivey,Danielle Walker,Brian White,Eduard Zuiderwijk,Carol Churcher,Michael A. Quail,Alan F. Cowman,C. M. R. Turner,Marie-Adèle Rajandream,Clemens H. M. Kocken,Alan W. Thomas,Chris I. Newbold,Chris I. Newbold,Bart Barrell,Matthew Berriman +56 more
TL;DR: This is the first monkey malaria parasite genome to be described, and it provides an opportunity for comparison with the recently completed P. vivax genome and other sequenced Plasmodium genomes.
Journal ArticleDOI
A comprehensive evaluation of rodent malaria parasite genomes and gene expression
Thomas D. Otto,Ulrike Böhme,Andrew P. Jackson,Martin Hunt,Blandine Franke-Fayard,Wieteke A. M. Hoeijmakers,Agnieszka A. Religa,Lauren Robertson,Mandy Sanders,Solabomi A. Ogun,Deirdre Cunningham,Annette Erhart,Oliver Billker,Shahid M. Khan,Hendrik G. Stunnenberg,Jean Langhorne,Anthony A. Holder,Andrew P. Waters,Chris I. Newbold,Arnab Pain,Matthew Berriman,Chris J. Janse +21 more
TL;DR: The greatly improved genome assemblies of PbA and PcAS, newly sequenced the virulent parasite P. yoelii YM genome, sequenced additional RMP isolates/lines and have characterized genotypic diversity within RMP species.
Journal ArticleDOI
Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans
Andrew P. Jackson,John Gamble,Tim Yeomans,Gary P. Moran,David S. Saunders,David A. Harris,Martin Aslett,Jamie F. Barrell,Geraldine Butler,Francesco Citiulo,David C. Coleman,Piet W. J. de Groot,Tim J. Goodwin,Michael A. Quail,Jacqueline A. McQuillan,Carol A. Munro,Arnab Pain,Russell T. M. Poulter,Marie-Adèle Rajandream,Hubert Renauld,Martin J. Spiering,Adrian Tivey,Neil A. R. Gow,Barclay G. Barrell,Derek J. Sullivan,Matthew Berriman +25 more
TL;DR: In this article, the authors sequenced the C. dubliniensis genome and compared it with the known C. albicans genome sequence and identified 168 species-specific genes including some hyphal-specific virulence factors, such as the aspartyl proteinases Sap4 and Sap5 and the proposed invasin Als3.
Journal ArticleDOI
Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species
Andrew P. Jackson,Andrew Berry,Martin Aslett,Harriet C. Allison,Peter Burton,Jana Vavrova-Anderson,Robert W. Brown,Hilary P. Browne,Nicola Corton,Heidi Hauser,John Gamble,Ruth Gilderthorp,Lucio Marcello,Jacqueline A. McQuillan,Thomas D. Otto,Michael A. Quail,Mandy Sanders,Andries J. van Tonder,Michael L. Ginger,Mark C. Field,J. David Barry,Christiane Hertz-Fowler,Christiane Hertz-Fowler,Matthew Berriman +23 more
TL;DR: How past VSG evolution indirectly determines the ability of contemporary parasites to generate novel variant antigens through recombination is demonstrated and suggest that the current model for antigenic variation in Trypanosoma brucei is only one means by which these parasites maintain chronic infections.
Journal ArticleDOI
The Genome Sequence of Trypanosoma brucei gambiense, Causative Agent of Chronic Human African Trypanosomiasis
Andrew P. Jackson,Mandy Sanders,Andrew Berry,Jacqueline A. McQuillan,Martin Aslett,Michael A. Quail,Bridget Chukualim,Paul Capewell,Annette MacLeod,Sara E. Melville,Wendy Gibson,J. David Barry,Matthew Berriman,Christiane Hertz-Fowler +13 more
TL;DR: This study provides the first estimate of intraspecific genomic variation within T. b.