A
Ao Ji
Researcher at University of California, Riverside
Publications - 8
Citations - 383
Ao Ji is an academic researcher from University of California, Riverside. The author has contributed to research in topics: Coelenterazine & Bioluminescence. The author has an hindex of 7, co-authored 8 publications receiving 284 citations. Previous affiliations of Ao Ji include University of Virginia.
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Journal ArticleDOI
Red-shifted luciferase–luciferin pairs for enhanced bioluminescence imaging
Hsien-Wei Yeh,Omran Karmach,Ao Ji,David Carter,Manuela Martins-Green,Hui-wang Ai,Hui-wang Ai +6 more
TL;DR: The development of red-shifted luciferins based on synthetic coelenterazine analogs and corresponding mutants of NanoLuc that enable bright bioluminescence are described and one pair showed superior in vitro and in vivo sensitivity over commonly used biolumeinescence reporters is adapted.
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Light Activation of Protein Splicing with a Photocaged Fast Intein
Wei Ren,Ao Ji,Hui-wang Ai +2 more
TL;DR: This work describes the recent result in engineering a photoactivatable intein compatible with living mammalian cells, genetically introduced into a highly efficient Nostoc punctiforme (Npu) DnaEintein and inserted into a red fluorescent protein (RFP) mCherry and a human Src tyrosine kinase to create inactive chimeric proteins.
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The N–B Interaction through a Water Bridge: Understanding the Chemoselectivity of a Fluorescent Protein Based Probe for Peroxynitrite
Zhijie Chen,Ziqi Tian,K. Kallio,April L. Oleson,Ao Ji,Dan Borchardt,De-en Jiang,S. James Remington,Hui-wang Ai +8 more
TL;DR: This study demonstrates the first example of tunable boron chemistry in a folded nonnative protein, which offers wide implications in designing selective chemical probes.
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A Sensitive Near-Infrared Fluorescent Sensor for Mitochondrial Hydrogen Sulfide
TL;DR: A novel near-infrared fluorescent probe, nimazide, is described by introducing sulfonyl azide to the core structure of a QSY-21 dark quencher and responding quickly to H2S, resulting in robust fluorescence turn-off changes.
Journal ArticleDOI
ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging.
TL;DR: A new family of ATP-independent bioluminescent reporters, which will have broad applications because of their ATP-independency, excellent biocompatibility, and superior in vivo sensitivity is engineered.