A
Apoorva K. Chandar
Researcher at Case Western Reserve University
Publications - 61
Citations - 1803
Apoorva K. Chandar is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 17, co-authored 41 publications receiving 1300 citations. Previous affiliations of Apoorva K. Chandar include Veterans Health Administration & University Hospitals of Cleveland.
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Journal ArticleDOI
Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis
Rohan Khera,Mohammad Hassan Murad,Apoorva K. Chandar,Parambir S. Dulai,Zhen Wang,Larry J. Prokop,Rohit Loomba,Michael Camilleri,Siddharth Singh +8 more
TL;DR: All active agents were associated with significant excess weight loss compared with placebo at 1 year and phentermine-topiramate, naltrexone-bupropion, and liraglutide, each associated with 5% weight loss at 52 weeks, were linked with the highest odds of adverse event-related treatment discontinuation.
Journal ArticleDOI
Association Between Inflammatory Bowel Disease and Vitamin D Deficiency: A Systematic Review and Meta-analysis.
Rita Del Pinto,Rita Del Pinto,Davide Pietropaoli,Davide Pietropaoli,Apoorva K. Chandar,Claudio Ferri,Fabio Cominelli +6 more
TL;DR: IBD is significantly associated with having higher odds of vitamin D deficiency, and well-designed randomized controlled trials and longitudinal studies are needed to further explain the role ofitamin D in IBD pathogenesis and its therapy.
Journal ArticleDOI
Comparative Effectiveness of Pharmacological Interventions for Severe Alcoholic Hepatitis: A Systematic Review and Network Meta-analysis.
Siddharth Singh,Mohammad Hassan Murad,Apoorva K. Chandar,Connie M. Bongiorno,Ashwani K. Singal,Stephen R. Atkinson,Mark Thursz,Rohit Loomba,Vijay H. Shah +8 more
TL;DR: In patients with severe AH, pentoxifylline and corticosteroids (alone and in combination with pentoxifyinglline or NAC) can reduce short-term mortality.
Journal ArticleDOI
Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus.
Helen Moinova,Thomas LaFramboise,Thomas LaFramboise,James Lutterbaugh,Apoorva K. Chandar,John A. Dumot,Ashley L. Faulx,Wendy Brock,Omar De la Cruz Cabrera,Kishore Guda,Jill S. Barnholtz-Sloan,Prasad G. Iyer,Marcia I. Canto,Jean S. Wang,Nicholas J. Shaheen,P N Thota,Joseph Willis,Amitabh Chak,Sanford D. Markowitz +18 more
TL;DR: A biomarker-based non-endoscopic method for detecting Barrett’s esophagus (BE) based on detecting methylated DNAs retrieved via a swallowable balloon-based esophageal sampling device and an efficient, well-tolerated, sensitive, and specific method of screening at-risk populations for BE is reported.
Journal ArticleDOI
The Effect of Endoscopic Surveillance in Patients With Barrett’s Esophagus: A Systematic Review and Meta-analysis
Don C. Codipilly,Apoorva K. Chandar,Siddharth Singh,Sachin Wani,Nicholas J. Shaheen,John M. Inadomi,Amitabh Chak,Prasad G. Iyer +7 more
TL;DR: In a systematic review and meta-analysis of the effects of surveillance in patients with Barrett's esophagus, surveillance as currently performed was associated with detection of earlier-stage EAC and may provide a small survival benefit.