A
Arne Schousboe
Researcher at University of Copenhagen
Publications - 527
Citations - 35724
Arne Schousboe is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Glutamate receptor & Glutamine. The author has an hindex of 97, co-authored 519 publications receiving 33871 citations. Previous affiliations of Arne Schousboe include Lundbeck & Biotec.
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Journal ArticleDOI
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
TL;DR: It is suggested that the large increase in the content of extracellular glutamate and aspartate in the hippocampus induced by the ischemic period may be one of the causal factors in the damage to certain neurons observed after ischemia.
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The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.
TL;DR: A main objective of this review is to endorse the view that the glutamate/GABA‐glutamine cycle must be seen as a bi‐directional transfer of not only carbon units but also nitrogen units.
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Control of GluR1 AMPA Receptor Function by cAMP-Dependent Protein Kinase
Tue G. Banke,Derek Bowie,Hey Kyoung Lee,Richard L. Huganir,Arne Schousboe,Stephen F. Traynelis +5 more
TL;DR: It is suggested that AMPA receptor peak response open probability can be increased by PKA through phosphorylation of GluR1 Ser845.
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Glial cells in (patho)physiology.
Vladimir Parpura,Michael T. Heneka,Vedrana Montana,Stéphane H. R. Oliet,Arne Schousboe,Philip G. Haydon,Randy F. Stout,David C. Spray,Andreas Reichenbach,Thomas Pannicke,Milos Pekny,Marcela Pekna,Robert Zorec,Alexei Verkhratsky,Alexei Verkhratsky +14 more
TL;DR: A review of brain operation in health and disease can be found in this article, which not only sheds new light on the brain operation, but also points to many unknowns, such as how gliotransmitters can modulate synaptic plasticity and cause changes in behavior.
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Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro
TL;DR: It is shown that essentially no increase in extracellular glutamate is seen under ischemia when the perfusion is performed using calcium‐free, cobalt‐containing perfusion media and the glutamate accumulatedextracellularly under ischemic conditions originates from transmitter pools in glutamatergic neurons.