Arnold T. Mosberg

TL;DR: It was shown that rats exposed to 6-h nose-only inhalation for 70 days at all three concentrations of glycerol exhibited minimal to mild squamous metaplasia of the epithelium lining the base of the epiglottis.

TL;DR: The introduction of exogenous material into the respiratory tract of laboratory animals in an experimental setting should be expected to result in certain changes and scientists must accept to interpret these changes so that toxic events may be separated from adaptive changes.

TL;DR: Comparison of the genotoxicity and cytotoxicity of mainstream cigarette smoke condensate from Eclipse and three vULT tobacco-burning cigarettes as well as the leading ultra low-"tar" (ULT) brandstyle (Marlboro Ultra Lights) under four smoking regimens demonstrate that the toxicity of CSC from Eclipse is significantly reduced relative to the activity of C SC from the tested vULT cigarettes and the Marlboro Ultra lights.

TL;DR: Overall, the study demonstrated a substantial reduction in the biological activity of smoke from the test cigarette when compared with the reference.

TL;DR: Comparative findings between A/J and rasH2 Tg mice suggest that the former may be overly sensitive to exposure-related stress, potentially influencing tumorigenic responses, and whole-body exposure appeared to be more effective for inducing statistical changes in tumor multiplicity and incidence compared to nose-only exposure.