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Arthur A. Vandenbark
Researcher at Oregon Health & Science University
Publications - 134
Citations - 7372
Arthur A. Vandenbark is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Experimental autoimmune encephalomyelitis & T cell. The author has an hindex of 41, co-authored 134 publications receiving 6920 citations. Previous affiliations of Arthur A. Vandenbark include Veterans Health Administration & United States Department of Veterans Affairs.
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Journal ArticleDOI
Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis.
TL;DR: This is the first report demonstrating the use of a synthetic T CR V-region peptide to induce specific regulatory immunity and has important implications for the regulation of human disease characterized by common TCR V-gene usage.
Journal ArticleDOI
Experimental Stroke Induces Massive, Rapid Activation of the Peripheral Immune System:
Halina Offner,Sandhya Subramanian,Susan M. Parker,Michael Afentoulis,Arthur A. Vandenbark,Arthur A. Vandenbark,Patricia D. Hurn +6 more
TL;DR: Data show for the first time that focal cerebral ischemia results in dynamic and widespread activation of inflammatory cytokines, chemokines, and CCR in the peripheral immune system.
Journal ArticleDOI
Cutting Edge: Estrogen Drives Expansion of the CD4+CD25+ Regulatory T Cell Compartment
Magdalena J. Polanczyk,Bryan Carson,Bryan Carson,Sandhya Subramanian,Michael Afentoulis,Arthur A. Vandenbark,Arthur A. Vandenbark,Steven F. Ziegler,Steven F. Ziegler,Halina Offner +9 more
TL;DR: The data suggest E2 promotes tolerance by expanding the regulatory T cell compartment by augmenting FoxP3 expression in vitro and in vivo, suggesting that high estrogen levels during pregnancy may help to maintain fetal tolerance.
Cutting Edge: Estrogen Drives Expansion of the CD4CD25 Regulatory T Cell Compartment 1
Magdalena J. Polanczyk,Bryan Carson,Sandhya Subramanian,Michael Afentoulis,Arthur A. Vandenbark,Steven F. Ziegler,Halina Offner +6 more
Journal ArticleDOI
Splenic Atrophy in Experimental Stroke Is Accompanied by Increased Regulatory T Cells and Circulating Macrophages
Halina Offner,Halina Offner,Sandhya Subramanian,Susan M. Parker,Chunhe Wang,Chunhe Wang,Michael Afentoulis,Anne D. Lewis,Arthur A. Vandenbark,Arthur A. Vandenbark,Patricia D. Hurn +10 more
TL;DR: New evidence is provided to support the contention that damage to the brain caused by cerebral ischemia provides a powerful negative signal to the peripheral immune system that ultimately induces a drastic state of immunosuppression caused by cell death as well as an increased presence of CD4+FoxP3+ regulatory T cells.