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Arthur M. Mandel

Researcher at Columbia University

Publications -  9
Citations -  1208

Arthur M. Mandel is an academic researcher from Columbia University. The author has contributed to research in topics: Pregnancy & Internal medicine. The author has an hindex of 5, co-authored 8 publications receiving 1069 citations.

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Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzyme.

TL;DR: In this article, the intramolcular dynamical properties of E. coli coliribonuclease H, including spin-lattic relaxation rate, spin-spin relaxation rate constants, and steady state nuclear Overhauser effects for the 15N nuclear spins were measured by using proton-detected heteronuclear NMR spectroscopy.
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Accuracy and precision of NMR relaxation experiments and MD simulations for characterizing protein dynamics

TL;DR: Comparisons suggest that the NMR and MD generalized order parameters for the backbone amide N—H bond vectors are of comparable accuracy for residues exhibiting motions on a fast time scale, thereby permitting more detailed dynamic characterization of biologically important residues by MD simulation than is sometimes possible by experimental methods.
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Differences in regional brain activation patterns assessed by functional magnetic resonance imaging in patients with systemic lupus erythematosus stratified by disease duration.

TL;DR: Analysis of activation patterns stratified by performance accuracy, differences in comorbid disease, corticosteroid doses or disease activity suggests that these observed differences are attributable to SLE effects on the central nervous system exclusive of vascular disease or other confounding influences.
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The frequency of non-epileptic spells in children: results of video-EEG monitoring in a tertiary care center.

TL;DR: The data highlights the importance of accurate diagnosis of NES toward the appropriate treatment of affected children, and indicates that crying spells/irritability and limb shaking in adolescents are more common in children with epilepsy than in those without epilepsy.