Assem Barakat

TL;DR: Results suggest that face-selective olefin coordination is the enantioselectivity-determining step, which is almost exclusively controlled by the element of planar chirality in the asymmetric aza-Claisen rearrangements.

TL;DR: The desired complex, subjected to thermal decomposition at low temperature of 400 ºC in an open atmosphere, revealed a novel and facile synthesis of pure NiO nanoparticles with uniform spherical particle.

TL;DR: These new derivatives of thieno[2,3-b]thiophene belong to a significant category of heterocyclic compounds, which have shown a wide spectrum of medical and industrial application and were evaluated for anti-cancer activity against PC-3 cell lines, in vitro antioxidant potential and β-glucuronidase and α- glucosidase inhibitory activities.

TL;DR: Compound 4k proved to retain a high cytotoxic activity and selectivity against colon cancer cells HCT-116, hepatocellular carcinoma, and prostate cancer cells PC-3 in comparison to cisplatin, and ligand Efficiency and Ligand Lipophilic Efficiency were evaluated and revealed that compound 4k had acceptable value.

TL;DR: The 1,3-dipolar cycloadditions of an azomethine ylide generated from isatin and thiazolidinecarboxylic acid to a series of 2,6-bis[(E)-arylmethylidene]cyclohexanones afforded new di-spiro heterocycles incorporating pyrrolidine and oxindole rings in quantitative yields and chemo- regio- and stereoselectively.