A
Atsushi Enomoto
Researcher at Nagoya University
Publications - 217
Citations - 10876
Atsushi Enomoto is an academic researcher from Nagoya University. The author has contributed to research in topics: Cancer & Organic anion transporter 1. The author has an hindex of 54, co-authored 189 publications receiving 9285 citations. Previous affiliations of Atsushi Enomoto include Laval University & Kyorin University.
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Journal ArticleDOI
Interaction of Human Organic Anion Transporters 2 and 4 with Organic Anion Transport Inhibitors
Atsushi Enomoto,Michio Takeda,Minoru Shimoda,Shinichi Narikawa,Yukari Kobayashi,Yasuna Kobayashi,Toshinori Yamamoto,Takashi Sekine,Seok Ho Cha,Toshimitsu Niwa,Hitoshi Endou +10 more
TL;DR: Results suggest that probenecid, 8-(noradamantan-3-yl)-1,3-dipropylxanthine, and betamipron, but not cilastatin, could inhibit hOAT4-mediated ES uptake in vitro, whereas probenECid alone could inhibit the hOat2-mediated PGF(2alpha) uptake.
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Interactions of Human Organic Anion Transporters and Human Organic Cation Transporters with Nonsteroidal Anti-Inflammatory Drugs
Suparat Khamdang,Michio Takeda,Rie Noshiro,Shinichi Narikawa,Atsushi Enomoto,Naohiko Anzai,Pawinee Piyachaturawat,Hitoshi Endou +7 more
TL;DR: It was suggested that the interactions of hOATs with NSAIDs are associated with the pharmacokinetics and the induction of adverse reactions of NSAIDs.
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Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells
TL;DR: IS induces ROS generation by upregulating Nox4, and the expression of osteoblast-specific proteins such as Cbfa1, ALP and osteopontin in HASMCs.
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Interactions of Human Organic Anion Transporters with Diuretics
Habib Hasannejad,Michio Takeda,Kentarou Taki,Ho Jung Shin,Ellappan Babu,Promsuk Jutabha,Suparat Khamdang,Mahmoud Aleboyeh,Maristela L. Onozato,Akihiro Tojo,Atsushi Enomoto,Naohiko Anzai,Shinichi Narikawa,Xiu-Lin Huang,Toshimitsu Niwa,Hitoshi Endou +15 more
TL;DR: HOAT1 may play an important role in the basolateral uptake of thiazides, and hOAT3 in the uptake of loop diuretics, and it was suggested that bumetanide taken up by hO AT3 and/or hOat1 is excreted into the urine by h OAT4.
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Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis
Yasuyuki Mizutani,Hiroki Kobayashi,Hiroki Kobayashi,Tadashi Iida,Naoya Asai,Atsushi Masamune,Akitoshi Hara,Nobutoshi Esaki,Kaori Ushida,Shinji Mii,Yukihiro Shiraki,Kenju Ando,Liang Weng,Seiichiro Ishihara,Suzanne M. Ponik,Matthew W. Conklin,Hisashi Haga,Arata Nagasaka,Takaki Miyata,Makoto Matsuyama,Tomoe Kobayashi,Tsutomu Fujii,Suguru Yamada,Junpei Yamaguchi,Tongtong Wang,Susan L. Woods,Daniel L. Worthley,Teppei Shimamura,Mitsuhiro Fujishiro,Yoshiki Hirooka,Atsushi Enomoto,Masahide Takahashi +31 more
TL;DR: Meflin is a marker of rCAFs that suppress PDAC progression, and in-situ hybridization analysis of 71 human PDAC tissues revealed that the infiltration of Meflin-positive CAFs correlated with favorable patient outcome and a mechanism for generating CAF heterogeneity.