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Atsushi Enomoto
Researcher at Nagoya University
Publications - 217
Citations - 10876
Atsushi Enomoto is an academic researcher from Nagoya University. The author has contributed to research in topics: Cancer & Organic anion transporter 1. The author has an hindex of 54, co-authored 189 publications receiving 9285 citations. Previous affiliations of Atsushi Enomoto include Laval University & Kyorin University.
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Journal ArticleDOI
The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia
Fusako Komoda,Takashi Sekine,Jun Inatomi,Atsushi Enomoto,Hitoshi Endou,Toshiyuki Ota,Takeshi Matsuyama,Tsutomu Ogata,Masahiro Ikeda,Midori Awazu,Koji Muroya,Isamu Kamimaki,Takashi Igarashi +12 more
TL;DR: It is demonstrated that homozygous W258X mutation is the predominant genetic cause of idiopathic renal hypouricemia in Japanese patients and their family members show relatively low levels of serum urate.
Journal ArticleDOI
Girdin phosphorylation is crucial for synaptic plasticity and memory : a potential role in the interaction of BDNF/TrkB/Akt signaling with NMDA receptor
Tsuyoshi Nakai,Taku Nagai,Motoki Tanaka,Norimichi Itoh,Naoya Asai,Atsushi Enomoto,Masato Asai,Shinnosuke Yamada,Ali Bin Saifullah,Masahiro Sokabe,Masahide Takahashi,Kiyofumi Yamada +11 more
TL;DR: The findings suggest that Girdin has two different functions in the hippocampus:Akt-independent neuronal migration and Akt-dependent NR2B phosphorylation through the interaction with Src, which is associated with synaptic plasticity in the hippocampal underlying memory formation.
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Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells
Keiko Maeda,Atsushi Enomoto,Akitoshi Hara,Naoya Asai,Takeshi Kobayashi,Asuka Horinouchi,Shoichi Maruyama,Yuichi Ishikawa,Takahiro Nishiyama,Hitoshi Kiyoi,Takuya Kato,Kenju Ando,Liang Weng,Shinji Mii,Masato Asai,Yasuyuki Mizutani,Osamu Watanabe,Yoshiki Hirooka,Hidemi Goto,Masahide Takahashi +19 more
TL;DR: It is reported that a cell surface and secreted protein, Meflin, is expressed in cultured MSCs, fibroblasts and pericytes, but not other types of cells including epithelial, endothelial and smooth muscle cells.
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Interactions of human organic anion as well as cation transporters with indoxyl sulfate.
Atsushi Enomoto,Michio Takeda,Kentarou Taki,Fumio Takayama,Rie Noshiro,Toshimitsu Niwa,Hitoshi Endou +6 more
TL;DR: It was predicted that human-OAT1 and human-WAT3 mediate the transport of indoxyl sulfate in vivo, and it was suggested thathuman-O AT1 andhuman- OAT3 are involved in the urinary excretion of ind oxyl sulfates, the exacerbation of renal dysfunction and the induction of uremic encephalopathy by indoxy sulfate.
Journal ArticleDOI
Girdin Is an Intrinsic Regulator of Neuroblast Chain Migration in the Rostral Migratory Stream of the Postnatal Brain
Yun Wang,Naoko Kaneko,Naoya Asai,Atsushi Enomoto,Mayu Isotani-Sakakibara,Takuya Kato,Masato Asai,Yoshiki Murakumo,Haruko Ota,Takao Hikita,Takashi Namba,Takashi Namba,Keisuke Kuroda,Kozo Kaibuchi,Guo Li Ming,Hongjun Song,Kazunobu Sawamoto,Masahide Takahashi +17 more
TL;DR: It is shown that mice lacking the actin-binding Akt substrate Girdin have profound defects in neuroblast chain migration along the rostral migratory stream (RMS), suggesting that GirdIn is an important intrinsic factor that specifically governs neuroblast Chain Migration along the RMS.