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Attila Patócs
Researcher at Semmelweis University
Publications - 219
Citations - 5815
Attila Patócs is an academic researcher from Semmelweis University. The author has contributed to research in topics: Germline mutation & Medicine. The author has an hindex of 35, co-authored 199 publications receiving 4977 citations. Previous affiliations of Attila Patócs include Cleveland Clinic & Case Western Reserve University.
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Journal ArticleDOI
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis
TL;DR: The pathways encompassing succinate as a metabolite or a signal and how these may interact in normal and pathological conditions are reviewed.
Journal ArticleDOI
Breast-Cancer Stromal Cells with TP53 Mutations and Nodal Metastases
Attila Patócs,Li Zhang,Yaomin Xu,Frank Weber,Trinidad Caldés,George L. Mutter,Petra Platzer,Charis Eng +7 more
TL;DR: Stroma-specific loss of heterozygosity or allelic imbalance is associated with somatic TP53 mutations and regional lymph-node metastases in sporadic breast cancer but not in hereditary breast cancer.
Journal ArticleDOI
Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis
Kevin Sweet,Joseph Willis,Xiao Ping Zhou,Carol J. Gallione,Takeshi Sawada,Pia Alhopuro,Sok Kean Khoo,Attila Patócs,Cossette Martin,Scott J. Bridgeman,John W. Heinz,Robert Pilarski,Rainer Lehtonen,Thomas W. Prior,Thierry Frebourg,Bin Tean Teh,Douglas A. Marchuk,Lauri A. Aaltonen,Charis Eng +18 more
TL;DR: Systematic molecular classification of 49 patients with unexplained hamartomatous or hyperplastic polyposis uncovered a potential novel susceptibility gene, ENG, for juvenilepolyposis, which should be considered routinely as organ-specific surveillance rests on defining syndromic diagnosis.
Journal ArticleDOI
Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes.
Ying Ni,Kevin Zbuk,Tammy Sadler,Attila Patócs,Glenn P. Lobo,Emily A Edelman,Petra Platzer,Mohammed S. Orloff,Kristin A. Waite,Charis Eng +9 more
TL;DR: Germline SDH mutations/variants occur in a subset of PTEN mutation-negative CS/CS-like individuals and are associated with increased frequencies of breast, thyroid, and renal cancers beyond those conferred by germline PTEN mutations.
Journal Article
A prospective, multicentre study to investigate the efficacy,
Moisés Mercado,F. Borges,Hakim Bouterfa,Tien-Chun Chang,A. Chervin,Andrew J. Farrall,Attila Patócs,Stephan Petersenn,Jan Podoba,M Safari,Joanna M. Wardlaw +10 more
TL;DR: In this paper, the efficacy, safety and tolerability of octreotide LAR (long-acting repeatable octereotide) in the primary therapy of acromegaly was evaluated.