A
Audrey Frachet
Researcher at University of Luxembourg
Publications - 2
Citations - 474
Audrey Frachet is an academic researcher from University of Luxembourg. The author has contributed to research in topics: Prebiotic & Synbiotics. The author has an hindex of 2, co-authored 2 publications receiving 323 citations.
Papers
More filters
Journal ArticleDOI
A microfluidics-based in vitro model of the gastrointestinal human-microbe interface.
Pranjul Shah,Joëlle V. Fritz,Enrico Glaab,Mahesh Desai,Kacy Greenhalgh,Audrey Frachet,Magdalena Niegowska,Matthew Estes,Christian Jäger,Carole Seguin-Devaux,Frederic Zenhausern,Paul Wilmes +11 more
TL;DR: The ability of HuMiX to recapitulate in vivo transcriptional, metabolic and immunological responses in human intestinal epithelial cells following their co-culture with the commensal Lactobacillus rhamnosus GG (LGG) grown under anaerobic conditions is demonstrated.
Journal ArticleDOI
Integrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer-Derived Cells.
Kacy Greenhalgh,Javier Ramiro-Garcia,Almut Heinken,Pit Ullmann,Tamara Jean Rita Bintener,Maria Irene Pires Pacheco,Joanna Baginska,Pranjul Shah,Audrey Frachet,Rashi Halder,Joëlle V. Fritz,Thomas Sauter,Ines Thiele,Serge Haan,Elisabeth Letellier,Paul Wilmes +15 more
TL;DR: The HuMiX gut-on-a-chip model was expanded to co-culture CRC-derived epithelial cells with a model probiotic under a simulated prebiotic regimen, and the multi-omic results were integrated with in silico metabolic modeling.